0.8mg Soloxine - Blue Tablet - each

This medication may only be supplied with a valid veterinary prescription, issued by your vet. You should only purchase this item if you have or are in the process of arranging such a prescription. See information bar for further details.

Presentation
Soloxine are small elliptical tablets containing L-Thyroxine Sodium. Scored on the face of each tablet, strength in milligrams to the right and the word SOLOXINE on the reverse. 0.1 mg yellow 0.2 mg orange 0.3 mg green 0.5 mg white 0.8 mg blue

Uses
Soloxine is used for the long term treatment of thyroid insufficiency in dogs. L-Thyroxine is a synthetic product chemically identical to the naturally occurring thyroid hormone `T4'. Its effect is slow in onset, but of long duration.

Dosage and administration
The dosage of Soloxine should be adjusted for the individual case based on the response of the patient and laboratory investigations, and should be administered daily. Pharmacokinetic trials demonstrate that once daily dosing with Soloxine gives higher blood levels than dividing the daily dose over the day. The commonly prescribed dose is 22 �g/kg bodyweight/day. This is frequently too low, and doses of up to 44 �g/kg bodyweight/day may be required. Appropriate laboratory tests should be conducted to confirm the diagnosis and ensure correct dosage of Soloxine. Soloxine is for oral administration.

Contra-indications, warnings, etc
Do not use Soloxine in dogs with thyrotoxicosis or uncorrected adrenal insufficiency. The effects of Thyroxine therapy are slow in being manifested. Administer Soloxine with caution to animals with clinically significant heart disease, hypertension or other complications for which a sharply increased metabolic rate might prove hazardous. Chronic overdosage will eventually lead to thyrotoxicosis, manifested by: panting, nervousness, tachycardia, aggressive behaviour, polyuria, polydipsia, polyphagia and weight loss. If you notice any serious effects or other effects not mentioned in the leaflet, please inform your veterinary surgeon. Operator warnings: Wash hands after using Soloxine. In case of accidental ingestion, seek medical advice immediately and show the doctor the leaflet. General precautions: For animal treatment only. Keep out of the reach and sight of children.

Pharmaceutical precautions
Do not store Soloxine above 25�C. Protect from light. Disposal: Dispose of used packaging in the household refuse. Unused product should be returned to the veterinary surgeon.

Legal category
Soloxine is a POM-V