|Active Ingredient:||Ivermectin and Praziquantel|
|Target Animal:||Horse (Equine)|
|Pet Prescription Required?:||No|
|Product Name:||Eqvalan Duo Horse Wormer - 1 Syringe|
|Pack Size:||Sold Individually|
Eqvalan Horse Wormer is an oral paste containing 15.5 mg/g ivermectin and 77.5 mg/g praziquantel. Each syringe contains 7.74g of paste.
For the treatment of mixed cestode (tapeworm) and nematode (roundworm) or arthropod (bot) infestations in horses.
The following parasites of horses are sensitive to the antiparasitic effects of EQVALAN DUO: Tapeworms: Anoplocephala perfoliata Large strongyles: Strongylus vulgaris (adults and arterial larval stages) Strongylus edentatus (adults and tissue larval stages) Strongylus equinus (adults) Triodontophorus spp. (adults) Triodontophorus brevicauda Triodontophorus serratus Craterostomum acuticaudatum (adults) Adult and immature (fourth-stage larvae) small strongyles or cyathostomes including benzimidazole-resistant strains: Coronocyclus spp. Coronocyclus coronatus Coronocyclus labiatus Coronocyclus labratus Cyathostomum spp. Cyathostomum catinatum Cyathostomum pateratum Cylicocyclus spp. Cylicocyclus ashworthi Cylicocyclus elongatus Cylicocyclus insigne Cylicocyclus leptostomum Cylicocyclus nassatus Cylicodontophorus spp. Cylicodontophorus bicornatus Cylicostephanus spp. Cylicostephanus calicatus Cylicostephanus goldi Cylicostephanus longibursatus Cylicostephanus minutus Parapoteriostomum spp. Parapoteriostomum mettami Petrovinema spp. Petrovinema poculatum Poteriostomum spp. Adult hairworms: Trichostrongylus axei Adult and immature pinworms: Oxyuris equi Adult third- and fourth-stage larvae of roundworms (ascarids): Parascaris equorum Microfilariae of neck threadworms: Onchocerca spp. Adult intestinal threadworms: Strongyloides westeri Adult large-mouth stomach worms: Habronema muscae Oral and gastric stages of bots: Gasterophilus spp. Adult and immature lungworms: Dictyocaulus arnfieldi
Dosage and administration
The recommended dose is 200 mcg ivermectin per kg bodyweight and 1mg praziquantel per kg bodyweight (corresponding to 1.29g of paste per 100kg bodyweight in a single treatment). Bodyweight and dosage should be accurately determined prior to treatment. The contents of one syringe will treat horses up to 600kg. Calibrated markings are provided at 100kg bodyweight intervals. The syringe should be adjusted to the calculated dosage by setting the ring on the appropriate place on the plunger. Parasite control program Veterinary advice should be sought on appropriate dosing programs and stock management to achieve adequate parasite control for both tapeworm and roundworm infestations. Dosing instructions EQVALAN DUO oral paste is for oral administration only. While holding the plunger turn the knurled ring on the plunger ¼ turn to the left and slide it so the stop ring is at the prescribed weight marking. Lock the ring in place by turning it ¼ turn to the right in order to bring the two arrows the one visible on the ring and the one on the plunger rod into alignment. Make sure the horse`s mouth contains no feed. Remove the cover from the tip of the syringe. Insert the syringe tip into the horse’s mouth at the interdental space and deposit the paste on the base of the tongue. Immediately raise the horse’s head for a few seconds after dosing and ensure that the paste is consumed.
Contra-indications warnings etc
Safety studies were not conducted in foals younger than 2 months of age nor in stallions therefore EQVALAN DUO cannot be recommended for use in these categories of animals. EQVALAN DUO has been formulated for use in horses only. Cats dogs especially Collies Old English Sheepdogs and related breeds or crosses and also turtles and tortoises may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: - Too frequent and repeated use of anthelmintics from the same class over an extended period of time. - Underdosing which may be due to underestimation of body weight misadministration of the product or lack of calibration of the dosing device (if any). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to macrocyclic lactones (which includes ivermectin) has been reported in Parascaris equorum in horses in the EU. Therefore the use of this product should be based on local (regional farm) epidemiological information about susceptibility of gastro-intestinal nematodes and recommendations on how to limit further selection for resistance to anthelmintics. Some horses with heavy infections of Onchocerca spp. microfilariae have experienced oedema and pruritus following treatment assumed to be the result of the death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable. In cases of heavy infestations with tapeworms signs of mild transient colic and diarrhoea may be observed. Following administration of EQVALAN DUO there have been rare reports of inflammation of the mouth lip and tongue which results in various clinical signs such as oedema hypersalivation erythema tongue disorder and stomatitis. These reactions have been transitory in nature appearing within 1 hour and abating within 24 to 48 hours following administration. In case of severe oral reactions symptomatic treatment is recommended. No undesirable effects related to treatment were observed in 2 month old horses treated with EQVALAN DUO at up to three times the recommended dose and in adult horses treated at ten times the recommended dose. Transient decreased food consumption increased body temperature and impairment of vision were noticed in horses treated twice with an ivermectin oral paste at ten times the recommended dose (i.e. 2 mg/kg b.w.). All changes disappeared within five days. No antidote has been identified; however symptomatic therapy may be beneficial. User warnings Wash hands after use. Do not smoke eat or drink while handling the product. For animal treatment only. This product may cause skin and eye irritation. Therefore the user should avoid contact of the product with the skin and eyes. In case of contact rinse immediately with plenty of water. In the case of accidental ingestion or eye irritation after contact seek medical advice immediately and show the package leaflet or the label to the physician. Use during pregnancy and lactation Ivermectin-praziquantel combination can be used after the first three months of gestation and during lactation. In the absence of clinical data in early pregnancy EQVALAN DUO can only be used in the first three months of gestation according to a risk benefit analysis by the veterinarian. Withdrawal periods Meat: 30 days. Do not use in mares producing milk for human consumption. Container disposal EXTREMELY DANGEROUS FOR FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used syringes. Dispose of any unused product and empty syringes in accordance with guidance from your local waste regulation authority. Pharmaceutical precautions Keep out of the reach and sight of children. Store in the original container. Replace the cap after use. Part used syringes can be kept for up to 2 years after first use but should be used by the expiry date printed on the packaging.
Eqvalan Duo Horse Wormer is a POM-VPS