Prascend for Horses
Prascend for Horses

1mg Prascend for Horses - Pergolide

What is Prascend for horses?
Prascend Tablets
contain 1mg Pergolide. 1mg Prascend is used as a treatment for cushings disease in horses. A small benign tumour in the pituitary gland causes an increased release of cortisol from the adrenal glands causing equine Cushing’s syndrome.

How does Prascend Equine work...

1mg Prascend for Horses - Pergolide

What is Prascend for horses?
Prascend Tablets
contain 1mg Pergolide. 1mg Prascend is used as a treatment for cushings disease in horses. A small benign tumour in the pituitary gland causes an increased release of cortisol from the adrenal glands causing equine Cushing’s syndrome.

How does Prascend Equine work?
Pergolide is a synthetic ergot derivative and is a potent dopamine receptor agonist. As with other dopamine agonists, pergolide inhibits the release of prolactin. In horses with PPID, pergolide is believed to exert its therapeutic effect by stimulating dopamine receptors, and has been shown to decrease the plasma levels of adrenocorticotropic hormone (ACTH), melanocyte stimulating hormone (MSH), and other pro-opiomelanocortin peptides?

What is Horse Prascend used for?
Prascend tablets are used to control equine Cushing's disease (also referred to as hyperadrenocorticism). Cushings disease in horses can cause many symptoms. Clasically horses become more hairy and require more clipping than usual. Affected horses often develop a pot-bellied type appearance and can develop fat pads around the face and eyes in particular. Cushingoid horses are also more prone to lameness, laminitis is a particular problem. Other symptoms include an increased thirst and appetite, increased urination and increased infections. For example, wounds may take longer to heal than would be expected. Clinical improvement with Prascend is expected within 6 to 12 weeks. Some horses may respond clinically at lower or varying doses, and it is recommended to titrate to the lowest effective dose per individual based on response to therapy, whether it is effectiveness or signs of intolerance. A small number of horses may require doses as high as 10 µg/kg per day. In these rare situations, appropriate additional monitoring should be implemented. ?

How is Prascend given?
Prascend
tablets may be administered orally by dissolving the tablet with a small amount of water and/or mixing with molasses or other sweetener; taking care to rinse the dosing apparatus with water to ensure entire dose of prascend is administered; use immediately. Most horses respond to prascend therapy and are stabilised at an average dose of 2 µg/kg.

How is horse Cushings diagnosed?
In some cases, vets may make a diagnosis of Cushings based simply on a clinical examination and an appreciation of the medical history of the horse or pony. In many cases however, your vet will want to take one or more blood samples from your horse in order to measure blood levels of various hormones or markers. The results of these tests can then be compared to "normal" ranges for the horse population, to confirm the presence of absence of the disease. Although a range of blood tests are available to assist the diagnosis and monitoring of cushings, the two most commonly used tests are: the Resting ACTH test – where a single blood sample is taken to measure the level of the hormone ACTH which is abnormally high in untreated cushings cases the Low dose Dexamethasone suppression test – where blood samples are taken before and after administration of a small dose of dexamethasone, to look for a "normal" response.

Prascend is available in 1mg tablet form

Prascend is a POM-V medication. A veterinary prescription must be provided prior to dispatch.

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