Advantix spot-on solution is used to treat fleas in dogs.
Advantix contains the active ingredients imidacloprid and permethrin and is available in the following strengths: Advantix Spot-On Solution for dogs up to 4 kg, Advantix Spot-On Solution for dogs of 4 kg up to 10 kg, Advantix Spot-On Solution for dogs of 10 kg up to 25 kg and Advantix Spot-On Solution for dogs of 25 kg and over
A Veterinary Pet Prescription is required for Advantix
Advocate is a spot-on treatment used to control internal and external parasites (fleas and worms) affecting dogs and cats.
One of the active ingredients in Advocate is absorbed through your pet's skin and travels around the body, treating internal parasites such as worms. A second ingredient transfers across the surface of the body and kills surface-living parasites such as fleas.
A Veterinary Pet Prescription is required for Advocate
Aludex Demodectic wash is a prescription-only pet medication used for the treatment of local and generalised demodectic mange and sarcoptic mange in dogs caused by mites.
Aludex 50 g/l Concentrate for cutaneous solution is clear emulsifiable concentrate for dilution and topical application containing 5% w/v amitraz as Amitraz. On dilution with water, Aludex forms an emulsion.
Aludex is used for the treatment of local and generalised demodectic mange and sarcoptic mange in dogs and is intended for external use only. Shake the container/bottle before use.
Repeat treatment at weekly intervals for 2 to 6 weeks. Do not use Aludex simultaneously with other ectoparasiticidal preparations. Wear waterproof gloves, apron and face shield when handling Aludex and wash all protective clothing thoroughly after use, including the inside of gloves.
A Veterinary Pet Prescription is Required for Aludex
The term “mange” is used to refer to a skin condition that is caused by the presence of parasitic mites, which can affect a whole host of animals including cats, dogs, horses, reptiles, wildlife such as foxes, and even humans. It is one of the easiest parasitic disorders to pass on from animal to animal, and as such, it can be hard to eradicate and keep from recurring, particularly if you keep several animals within the home, or your horse is stabled on a yard with others.
Mange is often connected with a general poor condition in pets, and in stray and wild animals, the condition is certainly rife. However, a diagnosis of mange certainly doesn’t automatically mean that an animal has been neglected; the condition can be picked up very easily, even by animals in excellent condition that are well cared for.
If you are concerned about a diagnosis of mange in your pet and want to learn more about the condition and what can be done about it, this article will cover some of the basics.
Mange is caused by a parasitic mite, which burrows into the skin and hair follicles of the animal, leading to irritation, soreness, loss of fur, and possibly, inflammation. It is generally very itchy for the affected animal, and will cause them to scratch and bother their skin obsessively, which can of course lead to problems in and of itself.
Mange in animals comes in two different forms: sarcoptic mange and demodetic mange respectively. While the result of an infestation with either type of mite will present with very similar symptoms, they are actually caused by two different families of mites.
Sarcoptic mange is also sometimes called canine scabies, although it is not exclusive to the dog. This type of mange is very infectious, and can be passed easily from dog to dog and to a variety of other animals as well. The mite responsible for sarcoptic mange is a type of burrowing mite called Sarcoptes scabiei canis.
Sarcoptic mange mites burrow into the top layers of the skin of the host animal, which leads to an allergic reaction that in its turn generates an intense pruritus or itchiness of the skin, as well as crusty skin, scab formation, and potentially, secondary infections. Loss of fur also often accompanies the condition.
Animals affected with sarcoptic mange must be kept in isolation from other animals until the condition is resolved, and special care must be taken with food bowls, bedding and other equipment used for the affected animal, as these too can harbour mites.
Demodetic mange is sometimes referred to by other names, such as red mange or demodicosis, and is caused by the Demodex canis mite. In some cases, small numbers of these mites can live on the skin of affected animals without causing any problems, and the natural immune system of the animal limits the development of the colony and keeps it in check.
However, for pets with a compromised immune system, or that are ill with another condition, the immune system may be unable to offer sufficient resistance to keep the mites in check, which can cause an outbreak on the skin that may be either localised or generalised.
If there are four or fewer affected spots on the skin, this is known as localised demodetic mange, while a systemic infection across the whole body is considered to be a generalised outbreak.
While sarcoptic mange is highly contagious between animals, demodetic mange is not actually normally contagious, other than potentially from a dam to their offspring. Most adult animals that are otherwise healthy tend to have a natural immunity that protects them from contracting demodetic mange.
How is mange diagnosed?
If an animal is afflicted with mange, this is usually fairly obvious as there will be sores, bald patches and inflamed areas on the skin, as well as intense itching. Your vet may need to take a skin scraping from an affected area for examination under a microscope, to identify the presence of the mites themselves.
However, microscopic examination is not 100% reliable, as low numbers of mites might mean that they do not show up under the microscope at all. Due to this, diagnosis of mange is often made on the basis of a physical examination alone.
How is mange treated?
There are a relatively wide range of options available when it comes to treating mange in animals, and your vet will discuss with you the best course of action for your own animal, based on your pet’s clinical history, the severity of the outbreak, and your own input.
Some of the most commonly used and most effective treatments for mange include:
If you suspect that your pet is affected with mange of either type, it is important to get a firm diagnosis as soon as possible, so that treatment can be begun promptly to offer relief to the afflicted animal, and minimise the chances of the condition spreading to other pets.
What are Antirobe Capsules?
Antirobe is an antibiotic made by Pfizer containing the active drug is Clindamycin.
How does Antirobe work?
Antirobe interferes with the ability of the bacteria to produce certains proteins which are essential for them to survive.
What can Antirobe be used for?
Antirobe is used in both dogs and cats primarily for abscesses, mouth infections and antibiotic cover for dental procedures. Antirobe can also be used to treat bone infections (osteomyelitis). Antirobe can also be used to treat skin infections in dogs.
How is Antirobe administered?
Antirobe is given orally in a capsule. The capsule can be given whole or opened and sprinkled onto food.
Antirobe should not be given to small animals such as rabbits and guinea pigs as it can predispose to severe infections in the gut. Vomiting and diarrhoea have been seen after administration. If this happens, discontinue treatment and contact your vet.
Antirobe capsules are available as either
25mg Antirobe Capsules,
75mg Antirobe Capsules,
150mg Antirobe Capsules or
300mg Antirobe Capsules
A Veterinary Pet Prescription is Required for Antirobe Capsules
What is Atopica?
Atopica (or cyclosporine A) is a pet prescription medication that can be prescribed by your vet for the treatment of itchy skin and ear conditions in dogs.
Atopic dermatitis, or atopy in dogs is similar to eczema in people and symptoms are generally first noticed when your dog is between one and three years of age, although in some cases, symptoms may even be noted in puppies. It is thought that as many as 1 in 10 dogs will suffer from atopy with varying degress of severity.
The symptoms of atopy can include itchy ears, chewing of the feet and the legs, an itchy groin, recurrent skin and ear infections. Animals may be affected in one or several regions of the body and the severity of skin disease varies considerably: some dogs become severely affected with widespread skin infections and significant hair loss whilst other dogs may develop mild seasonal skin irritation.
How does Atopica Work?
Atopica specifically targets the immune system cells involved in the allergic response. It contains cyclosporine A, an immunomodulator.
What can Atopica be used for?
Atopica is proven to significantly relieve itchy skin and studies suggest that it is highly effective and improves the quality of life for many dogs. In fact, the vast majority of pet owners would recommend Atopica to a friend. It is generally possible to reduce the dose of atopica as time goes by.
Atopica is only available on prescription and if you suspect your pet is suffering from atopy, it is important that you see your Vet who will be able to diagnose the condition and rule out other causes of skin irritation such as ectoparasites, infection or food allergies.
How is Atopica Administered?
Atopica Capsules are given orally, usually once a day
Atopica is available in the following strengths:
10mg Atopica Capsules,
25mg Atopica Capsules
50mg Atopica Capsules
100mg Atopica Capsules
Atopica for Cats (Oral Solution)
A Veterinary Prescription is Required for Atopica
Atopic dermatitis is the term used to refer to a chronic irritation and inflammation of the skin that is caused by allergies, which can in turn be triggered by a wide variety of different things. Allergies in pets such as dogs and cats can be problematic, as they tend to flare up time and again, and it can be difficult to ascertain the exact trigger or allergenic factor that leads to the condition.
Allergies can be caused by a whole host of things, including common household substances, some ingredients in food, pollen, dust mites, and many other things too, and even if you can find the culprit that is causing the problem, keeping your pet from exposure to their particular trigger can be difficult in itself.
Pets such as dogs and cats that are affected with atopic dermatitis will usually become symptomatic by the time they reach six months of age, although it can take up until the animal is two or three years old for the condition to become very pronounced.
The symptoms of atopic dermatitis
The symptoms of atopic dermatitis may be seasonal, or come and go for other reasons. They also tend to progressively worsen with age, and may affect certain areas of the body in isolation. Some of the most common areas of the body that can be affected with atopic dermatitis are:
• Behind the ears.
• Around the ankles.
• In the armpits.
• Around the groin.
• Between the toes.
• Around the face and muzzle.
Symptoms of atopic dermatitis in affected areas include:
• Sore or inflamed areas of skin.
• Itching, rubbing, biting or pawing at the affected areas.
• In severe cases, bald patches may develop due to obsessive rubbing and scratching.
What causes atopic dermatitis?
Atopic dermatitis often has a hereditary element to it, and if the ancestors of the affected animal also suffered from allergies and sensitivities, they stand an exponentially higher chance of passing such sensitivities onto their offspring.
A huge range of factors can trigger atopic dermatitis due to a hypersensitivity to their presence, and some of the most common allergenic triggers in cats and dogs include:
• Pollens and other protein particles.
• Dust mites.
• Dander from other animals.
• Mould spores.
• Ingredients in commercial pet foods, or other food allergies.
Diagnosing atopic dermatitis
In order to begin to tackle the condition, you will need to take your pet along to your vet, to try to find the root of the allergy and work out a plan for what can be done to tackle it. There are various ways to go about this, including running serologic allergy tests, intradermal testing, exposure testing, and removing certain elements from the household to see if the allergies improve.
However, atopic dermatitis can be a tricky condition, and it is not always possible to definitively identify the cause of any given pet’s triggering compounds.
Are some breeds particularly predisposed to atopic dermatitis?
While any cat or dog, pedigree or otherwise, can potentially have an allergy to something or several somethings, some breeds of dog appear to be particularly susceptible to the condition, and more likely to develop the condition than others. Within cats, the condition is not generally connected to any particular breeds.
The Shar-Pei dog is one breed that is particularly prone to skin problems such as atopic dermatitis, and several other breeds including the West Highland Terrier, Bulldog, Golden Retriever, Labrador Retriever and the Dalmatian are some others.
How is atopic dermatitis treated?
How atopic dermatitis can be treated and tackled largely depends on what is found to be causing the condition, if this can be ascertained. In some cases, you vet may need to work with your pet long term using a method called hyposensitisation therapy, which will reduce the effect that allergenic triggers have on your pet, but can take up to a year to reach peak effectiveness.
Various other options available to your vet include the administration of antihistamines to reduce the effect that the allergy has on your pet, using a product such as Atopica to supress the body’s immune response to the allergenic trigger, or the prescription of corticosteroids to support the body’s natural responses.
Topical treatments such as baths, sprays or lotions may also be recommended to provide relief from the itching.
Can atopic dermatitis be cured?
Atopic dermatitis is a lifelong condition that will tend to come and go, being worse at times than others, and often appearing to go into total remission for long periods of time too. However, the condition rarely goes away entirely, and while you may be able to reduce or eliminate your pet’s exposure to the things that trigger a flare-up of the condition, this does not mean that you can resolve your pet’s reaction to them, nor “cure” their allergy entirely.
What is Baytril?
Baytril Flavour Tablets are light brown round flavoured tablets made by Bayer containing 15mg Enrofloxacin for oral administration to dogs and cats. Baytril Flavour Tablets 50mg and 150mg are light brown to brown slightly marbled round scored flavoured tablets containing 50mg or 150mg enrofloxacin for oral administration to Dogs. Baytril Flavour Tablets are a synthetic broad spectrum antimicrobial substance (antibiotic) belonging to the fluoroquinolone group of antibiotics.
How does Baytril Work?
Baytril is bactericidal in action and effective against many gram positive and gram negative bacteria and mycoplasmas.
What can Baytril be used for?
Baytril Tablets are for use in dogs and cats in the treatment of bacterial infections of the alimentary respiratory and urogenital tracts skin secondary wound infections and otitis externa where clinical experience supported where possible by sensitivity testing of the causal organism indicates enrofloxacin as the drug of choice.
How is Baytril administered?
Baytril is given orally once daily or as a divided dose twice daily for 3 to 10 days with or without food
Baytril Flavour Tablets are available in the following strengths: 15mg Baytril, 50mg Baytril and 150mg Baytril
A Veterinary Pet Prescription is required for Baytril Tablets
What is Caninsulin for dogs?
Caninsulin is a form of intermediate-acting insulin that is derived from pigs. Caninsulin for dogs can be administered to dogs or cats suffering from the condition, diabetes mellitus and acts to lower blood sugar levels. Caninsulin is a POM-V category medicine that is only available with a written pet prescription from your Vet. Online pet pharmacies are only able to supply this medicine upon receipt of the prescription.
How does Caninsulin injection for dogs work?
Canine Insulin treats a condition known as diabetes mellitus. Diabetes is caused by an absolute or relative lack of insulin. This means that the pancreas may be unable to produce sufficient insulin to control blood sugar levels, or that the insulin produced in unable to have any effect upon the body (something known as insulin resistance). Some conditions can make an animal more likely to develop diabetes, for example, pancreatic inflammation or pancreatitis can destroy the ? islet cells within the pancreas, responsible for the production of insulin. Some conditions can cause your pet’s immune system to behave abnormally and cause destruction of the pancreatic cells responsible for insulin production.
In human medicine, when diabetes is caused by reduced insulin production from the pancreas, it is termed type 1 diabetes. In comparison, being over-weight or obese can increase the likelihood that the insulin naturally produced by the pancreas will not work properly and be ineffective – insulin resistance. This form of diabetes is termed type 2 in human patients.
High blood sugar levels cause glucose to leak into the urine and affected animals often: drink excessively, urinate excessively, lose weight, often appear hungrier, especially in the early course of the disease, become more prone to infections, e.g. urinary infections, skin infections. In circumstances where diabetes has been affecting an animal for a prolonged period of time, animals may: develop cateracts (mainly in dogs), develop neurological conditions (mainly in cats), become rapidly ill and stop eating, vomit, become lethargic and depressed or even collapse as they develop a condition known as diabetic ketoacidosis. If your pet starts showing any of these signs, it is essential that you visit your vet in order to rule out many other conditions that may have similar symptoms
What is Caninsulin used for?
The active ingredient in Caninsulin is a purified form of pig insulin, produced by the beta islet of langerhans cells, found within the pig’s pancreas. Dog Insulin triggers an anabolic state in which carbohydrates, proteins and fat is produced. Insulin allows glucose, obtained from food or by the breakdown on protein or glycogen, to be taken up into cells. Glucose is required in relatively higher quantity by the liver, brain and adipose tissue. Diabetes therefore allows glucose to reach higher levels within the blood stream. In diabetic dogs, the action of Caninsulin in blood glucose concentrations, following subcutaneous administration peaks at about 4-8 hours post-injection and lasts for 14-24 hours. In diabetic cats the action of Caninsulin on blood glucose concentrations after subcutaneous administration peaks at about 4-6 hours and lasts for 8-12 hours post-injection.
How is Caninsulin administered?
Caninsulin is given by subcutaneous injection (under the skin). Insulin must be given using the specially designated caninsulin syringes (with red caps). If different syringes are used, the dose of insulin being given to the animal will differ and could potentially cause life-threatening consequences. Caninsulin can also now be delivered using the Vet Pen that makes the process of delivering insulin to your pet simpler and more accurate. It is important that insulin is stored correctly (in the fridge at between 2-8 degrees C) and is only gently agitated (not shaken as this damages the insulin). Dog Insulin should only be given if your dog is eating normally and seems well. If your diabetic dog seems unwell, you should consult a Vet immediately.
Caninsulin is available as a white or nearly-white suspension, in 2.5ml or 10ml vials or as a vet pen.
A Veterinary Prescription is Required for Caninsulin
** PLEASE NOTE - We cannot deliver Caninsulin outside the UK as we cannot guarantee it will stay refrigerated during shipping.
Diabetes is a condition that can affect all sorts of animals, including dogs as well as people. While diabetes is slightly more common in cats than in it is dogs, it is estimated that around one in every five hundred dogs will be diagnosed with diabetes at some stage of their lives, and a diagnosis of diabetes can be very concerning for the owners of such dogs.
However, diabetes can usually be successfully managed to allow your dog to lead an otherwise healthy and happy life, and it is worth finding out more about some of the basics of the condition so that you can spot the potential symptoms, and understand the terminology that your vet will use to explain the condition to you.
Diabetes is a condition caused by irregularities of the body’s insulin levels, which are essential to break down the carbohydrates from food into glucose. Glucose is then processed in the intestine, to provide essential fuel for life. How the body’s glucose is regulated and broken down is controlled by a hormone called insulin, which is itself produced by the dog’s pancreas.
Diabetes comes in two forms: Type one and type two.
In type one diabetes, the pancreas simply does not produce enough insulin to process glucose properly, while in type two diabetes, the pancreas produces insulin, but the body is unable to sufficiently process it to regulate glucose on its own.
The symptoms of diabetes in dogs
Diabetes is very rarely asymptomatic, and usually comes accompanied by a range of symptoms and warning signals that will progressively worsen over time. These symptoms tend to come in combination with each other, and dog owners should look out for the following signs of a problem:
• Drinking a lot of water.
• Excessive urination.
• Loss of weight and condition for no obvious reason.
• Lethargy, listlessness and a loss of interest in exercise and normal play.
Diagnosing canine diabetes
If you are concerned about any of the above symptoms, it is vital to take your dog along to the vet to be checked out, as the earlier that they are diagnosed and treatment begins, the better your dog will fare in the long run.
When you take your dog along to the vet and explain their symptoms, your vet will run a couple of tests on their blood and urine, which will usually produce a definitive diagnosis in a short period of time. If your vet does confirm diabetes, they will usually begin treatment for the condition promptly, and need to see your dog several times to monitor their blood: glucose balance and work out the best form of treatment.
Living with a diabetic dog
Diabetes cannot be cured or permanently corrected, and the condition will require ongoing management for the duration of your dog’s life. Managing diabetes for the long term involves correcting the body’s insulin imbalance or lack of production, and working to minimise any side effects or other complications that can arise because of the condition.
Diabetic dogs will generally need to be prescribed a special diet, and in some cases, this alone is sufficient to keep the condition under control, along with regular monitoring of their blood: glucose levels with a special device such as the AlphaTrak 2 glucose monitoring system for use with test strips.
However, many diabetic dogs will also require the supplemental administration of insulin, which comes in the form of an injectable compound that your vet will teach you to administer to your dog at home. A special form of insulin that is designed to meet the needs of the diabetic dog, such as Caninsulin, is the usual recommendation of veterinary professionals.
Generally, diabetic dogs need to be injected twice per day when they have their meals, and you will also need to learn how to monitor your dog’s blood: glucose levels, as well as arrange regular visits to your vet to ensure that the condition is being kept under control and not having any adverse side effects on your dog.
It is also vital to keep your dog’s weight within healthy parameters, as obesity can actually lead to diabetes developing, and worsen the condition and its effects on the dog after diagnosis.
Are some breeds of dog predisposed to diabetes?
Any breed of dog can theoretically develop diabetes, but it is more common in some breeds than others. The Cairn terrier, Samoyed, Poodle and Yorkshire terrier are just four breeds that seem to have an elevated chance of developing diabetes at some point in their lives.
Diabetes is also much more common in female does than in males, with around 70% of all cases of canine diabetes being diagnosed in bitches. Certain conditions such as Cushing’s disease can also elevate the risk factors for your dog developing diabetes too, as can long term administration of certain medications such as steroids, and so such dogs much be especially carefully monitored for the early signs of the condition.
Cefaseptin tablets are used for canine pyoderma caused by the bacteria Staphylococcus intermedius. Canine pyoderma is a common skin infection in dogs and can cause inflammation in and around the hair follicle, hair loss and itching in some cases.
Cefaseptin contains the active ingredient Cefalexin
A Veterinary Pet Prescription is required for Cefaseptin
Cephacare Tablets are a semi-synthetic bactericidal antibiotic which is is active against a wide range of Gram-positive and Gram-negative bacteria in cats and dogs
Cephacare contains the active ingredient Cefalexin and is availabe in the following strengths: 50mg Cephacare, 250mg Cephacare and 500mg Cephacare
A Veterinary Pet Prescription is required for Cephacare
Cephorum Tablets are a broad-spectrum cephalosporin antibiotic with bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria in dogs.
Cephorum contains the active ingredient Cefalexin and is available in the following strengths: 250mg Cephorum and 500mg Cephorum
A Veterinary Pet Prescription is required for Cephorum
What are Cerenia travel sickness tablets for dogs?
Cerenia tablets are used to treat vomiting in dogs and prevent travel sickness. Cerenia dog tablets are POM-V (prescription only medicine) category medicines and as such can only be dispensed upon receipt of a valid vet prescription. Cerenia contains the active ingredient, Maropitant.
How do Cerenia tablets work?
Cerenia tablets work in the brain as an antagonist of substance P at the NK1 receptor and is effectie against vomiting caused by central and peripheral stimuli. Cerenia tablets are often used in the clinic in cases where other medicines such as metoclopramide or emeprid have not been effective. Cerenia can be injected (although this can sometimes be a little uncomfortable for the patient) or given as oral tablets.
When are Cerenia tablets given?
Cerenia can be given when dogs start vomiting for a number of reasons. The majority of the time, dogs start vomiting when they eat material they find on walks. This vomiting is often short-lived and cerenia can help get the dog better, faster. Cerenia can also be given in cases of pancreatitis, gastritis, infection (e.g. parvoviral infection or pyometra) or at the same time as cancer chemotherapy to reduce occurrence of vomiting. Cerenia is given at a dose rate of 1mg/kg if injected subcutaneously, 2mg/kg if given orally or 8mg/kg for the treatment of travel sickness. Very occasionally, cerenia can cause transient vomiting when given at the higher dose rate. This can be overcome by administering the medicine with a light meal.
Cerenia is available in the following strengths:
A Veterinary Pet Prescription is Required for Cerenia
Clavaseptin Tablets are used for the treatment or adjunctive treatment of periodontal infections in dogs and cats caused by bacteria susceptible to amoxicillin in combination with clavulanic acid
Clavaseptin contains the active ingredients Amoxicillin and Clavulanic acid and is available in the following strengths: 50mg Clavaseptin, 250mg Clavaseptin and 500mg Clavaseptin
A Veterinary Pet Prescription is required for Clavaseptin
Clindacyl is used for the treatment of infected wounds abscesses, superficial pyoderma and oral cavity/dental infections
Clindacyl contains the active ingredient Clindamycin and is available in the following strengths: 25mg Clindacyl, 75mg Clindacyl, 150mg Clindacyl and 300mg Clindacyl
A Veterinary Pet Prescription is required for Clindacyl
Clomicalm is used as an aid in the treatment of separation-related disorders in dogs manifested by destruction and inappropriate defecation and urination
Clomicalm contains the active ingredient Clomipramine hydrochloride and is available in the following strengths: 5mg Clomicalm, 20mg Clomicalm and 80mg Clomicalm
A Veterinary Pet Prescription is required for Clomicalm
Comfortis flea tablets have revolutionised flea prevention in dogs. Traditionally, flea prevention in dogs is achieved by using shampoos and washes, sprays, flea collars and spot-on formulations. The problem with these topical products is that many dogs are resistant to being bathed and do not like having spot-on liquids applied to their skin. Additionally, many shampoos, washes and sprays do not have long durations of action allowing fleas from the environment to re-infest the dog.
Comfortis tablets for dogs are designed for the treatment and prevention of flea infestations. Comfortis has been available for many years in Australia and in the USA but has only recently been licensed in the UK. The beauty of medicating dogs with Comfortis is that owners no longer need to spend hours contending with messy baths or topical medications. With the addition of this tablet into the dog's food, fleas are killed for up to 4 weeks. This also means that dogs can go swimming immediately following application and be bathed with other medicated or non-medicated shampoos without the fear of washing the flea treatment away.
Comfortis tablets should always be given with food.
A Veterinary Pet Prescription is required for Comfortis Flea Tablets
Treating fleas with Comfortis
Comfortis is a highly effective oral flea treatment agent for dogs and cats, which provides protection against flea infestations for up to one month after treatment. Comfortis is an alternative to spot-on treatments or sprays and powders that can prove both messy and potentially toxic to the environment, as well as washing away with rain and baths.
What is Comfortis?
Comfortis is a palatable, beef-flavoured tablet designed to kill fleas and flea eggs for up to one month after treatment. Comfortis starts working in just half an hour, and the active ingredient in Comfortis, Spinosad, is environmentally friendly and naturally occurring, unlike many of the alternative toxic anti-parasitic products available for topical application.
How does Comfortis work?
The active ingredient in Comfortis, Spinosad, is an insecticide compound produced from chemicals that naturally occur in some forms of bacteria. Due to this it is classed as a natural product, and in many countries, has received organic certification. Spinosad is a neurotoxin to parasites such as fleas, which means that the compound destroys the parasite’s nerve tissue, killing both adult fleas and their larvae, and preventing their ability to reproduce.
Spinosad is safe for use in both dogs and cats when administered at the appropriate dosage and under veterinary guidelines, and Comfortis has undergone extensive clinical trials in both the UK and the USA to ascertain its effectiveness and safety for pets.
What animals can take Comfortis?
Comfortis can be prescribed for either cats or dogs, with tablets available in various different sizes to suit the needs of different sizes of pets. Comfortis should only be administered to the animal for which it has been prescribed.
Comfortis can be prescribed for dogs over the age of 14 weeks and weighing over 3.3lb, or for cats over the age of 14 weeks and weighing over 2lb.
How is Comfortis given?
Comfortis is given in tablet form, administered orally. The tablets are beef flavoured and palatable to cats and dogs, and can be chewed. If your pet will not voluntarily accept the pill, however, it can be given whole as you would with other tablet medications, and does not need to be chewed to prove effective. The tablets vary in size depending on the size of the animal for which they are prescribed.
Just one tablet of the appropriate size is required to provide a full month’s protection against fleas.
In order to maximise the effectiveness of the tablet, Comfortis should be given with food to ensure its rapid digestion. In the unlikely event that your pet vomits within an hour of dosage, another dose should be given to ensure protection. Comfortis should be given regularly on a monthly basis year-round, in order to ensure its efficacy at protecting your pet from fleas.
What are the advantages of Comfortis?
Comfortis is a natural product that is extremely well tolerated in cats and dogs, and is highly unlikely to produce any undesirable side effects such as vomiting, diarrhoea or digestive upsets. The tablet is palatable, chewable and does not taste bitter, making it well received by most pets, including those that will usually avoid taking oral medications of other types.
Comfortis gets to work in just thirty minutes, acting quickly to kill fleas and flea eggs on your pet, and halting their reproductive processes. It also offers many advantages over and above external products such as spot on treatments and powders and sprays.
Pets do not need to be isolated after treatment to keep them from transferring a surface treatment product onto people or other animals, and there is no danger of them licking the residue of such treatment products off their skin. Because Comfortis is an orally administered product, localised sensitivities and skin irritations that can present in some pets treated with topical products are also prevented, making it particularly suitable for pets that are prone to skin conditions or sensitivities.
Comfortis remains active for the entire month, and will not wash off in the rain or if you need to bathe your pet. Added to this, the active ingredient in Comfortis is highly effective against fleas at all stages of the lifecycle, and unlike some topical products, is not a product to which fleas in certain areas of the country have built up a resistance, limiting the efficacy of the product.
How do I get Comfortis for my pet?
Comfortis is a POM-V medication, which means that it can only be provided with a veterinary prescription. Once your vet has approved Comfortis for your pet, you can order online from us with your prescription.
Cortavance is cutaneous spray solution for symptomatic treatment of inflammatory and pruritic dermatoses in dogs
Cortavance contains the active ingredient Hydrocortisone aceponate and is available in the following strengths: 76ml Cortavance Spray
A Veterinary Pet Prescription is required for Cortavance
What is Bisolvon power
Bisolvon power contains the active ingredient bromhexine hydrochloride. Bisolvon sachets are used as an aid to the treatment of respiratory disease in cattle, pigs, dogs and cats where mucus is a complicating factor. Bisolvon is a prescription-only medication and as such may only be obtained upon receipt of a valid Vet Prescription.
How do Bisolvon sachets work?
Bisolvon is known as a mucolytic. This medication causes the thick mucous that may develop during the course of respiratory disease to break down into a thinner phlegm that can subsequently be coughed up.
What are the symptoms of lung disease in animals?
Respiratory disease in dogs can present in a number of different ways. Sometimes dogs will cough or show increased respiratory rate and effort. Some will appear to use their tummy as bellows in order to meet their oxygen demands. Affected dogs may seem more lethargic or depressed and may tire more easily. Cats respond to respiratory disease slightly differently. Cats are less likely to cough than dogs and often only display overt signs of respiratory compromise later in the course of the disease. Signs to look out for are increased breathing rates, increased breathing effort and open-mouthed breathing. Cats that pant or breathe through their mouth are often suffering from some degree of respiratory embarrassment and veterinary attention should be sought immediately.
How does Bisolvon powder help with respiratory disease in animals?
Bisolvon helps with wheezes and rattles in the chest by clearing the bronchioles of thick mucous, allowing the phlegm to be coughed up and swallowed.
Bisolvon is available as 5g sachets for dogs, cats, pigs and cows.
A Veterinary Prescription is Required for Bisolvon
What is Benazecare?
Benazecare Tablets are pale yellow film-coated divisible oval tablets manufactured by Animalcare. Each Benazecare tablet contains either 5mg or 20mg benazepril hydrochloride.
How do Benazecare Tablets work?
After oral administration Benazecare is rapidly absorbed from the gastrointestinal tract and hydrolysed into benazeprilat a highly specific and potent inhibitor of angiotensin converting enzyme (ACE). Benazeprilat produces significant inhibition of plasma ACE activity for more than 24 hours after a single dose in both dogs and cats. Inhibition of ACE leads to a reduced conversion of inactive angiotensin I into angiotensin II and therefore reduction in the effects mediated by angiotensin II including vasoconstriction of both arteries and veins retention of sodium and water by the kidney and remodelling effects (including pathological cardiac hypertrophy and degenerative renal changes).
What is Benazecare used for?
Benazecare Tablets are indicated for the treatment of congestive heart failure in dogs and the treatment of chronic renal insufficiency in cats. In dogs with heart failure Benazecare lowers the blood pressure and volume loading effect on the heart. In cats with renal insufficiency Benazecare reduces the protein loss in urine and normalises the elevated glomerular capillary pressure and reduces systemic blood pressure. Reduction in glomerular hypertension retards the progression of kidney disease by inhibition of further damage to the kidneys. Benazecare has been shown to increase the appetite quality of life and the survival time of cats particularly in advanced disease.
How is Benazecare administered?
In both dogs and cats, Benazecare should be given orally once daily with or without food. The duration of treatment is unlimited
Benazecare is available in strengths of 5mg Benazecare for Cats & Dogs and 20mg Benazecare for Dogs
A Veterinary Pet Prescription is Required for Benazecare
Cardisure (Pimobendan) is available in capsule and palatable tablet form and in the following strengths: 1.25mg Cardisure, 2.5mg Cardisure, 5mg Cardisure & Cardisure 10mg.
Cardisure is a drug that is often prescribed for dogs to treat a range of heart conditions and is associated with significantly improved survival times.
How Does Cardisure Work?
Cardisure opens up, or dilates the blood vessels that carry blood to and from the heart. This means that the heart doesn't have to work quite as hard to supply the body with oxygen. Cardisure also improves the ability of your dog's heart to act as a pump and improves the contractility of the heart muscle.
How will Cardisure Help my Dog?
Cardisure can help reduce the signs of heart failure, lead to a less tired and more active dog and significantly increase the lifespan of dogs in congestive heart failure. Owners generally report that their dog's quality of live dramatically improves following treatment with Cardisure. A recent global trial called QUEST showed how Cardisure can help prolong the life of dogs suffering from heart failure relating to underlying mitral valve disease. Another study documented the way in which Cardisure can prolong the life of Dobermans, suffering from dilated hearts (or DCM).
Are there any side effects that my dog might experience whilst taking Cardisure?
Cardisure is generally tolerated extremely well. On rare occasions, gastrointestinal side-effects may be seen such as vomiting or diarrhoea. If this happens or you are concerned about your dog for any reason, please contact your vet for advice. Cardisure is used for the treatment of canine congestive heart failure originating from dilated cardiomyopathy or valvular insufficiency (mitral and/or tricuspid regurgitation).
When Cardisure is used in cases of valvular insufficiency in conjunction with frusemide the product has been shown to improve the quality of life and extend life expectancy in treated dogs.
A Veterinary Pet Prescription is Required for Cardisure
What is Canaural?
Canaural is a yellow oily suspension containing 2 antibiotics; Diethanolamine fusidate, Framycetin sulphate, an anti-fungal agent; Nystatin and an anti-inflammatory agent; Prednisolone
How does Canaural work?
Canaural is effective against the micro-organisms commonly associated with otitis externa (inflammation of the ear) including the ear mite Otodectes cynotis
What can Canaural be used for?
Canaural is specifically formulated for the treatment of otitis externa in Dogs and Cats.
How is Canaural administered?
Canaural Drops are applied twice a day the affected ear (or according to your Vet's instructions) usually for a minimum of 7 days.
Canaural Drops are available as 15ml Canaural and 25ml Canaural Bottles
A Veterinary Pet Prescription is Required for Canaural Ear Drops
What are Corvental D capsules?
Corvental D contains a medicine called theophylline. Corvental D is available as 100 mg, 200 mg or 500 mg capsules. Corvental is often used for the treatment of bronchitis and congestive heart failure in the dog. This medicine is only available on prescription, issued by your vet. This prescription will need to be examined by the online pet pharmacy prior to dispatch of the medication.
What are Corvental D tablets used for?
Corvental capsules are prescribed for the treatment of congestive heart failure and for chronic bronchitis in dogs. Congestive heart failure occurs when the heart begins to fail and fluid can then start to accumulate inside the chest or within the abdomen. Common symptoms include reluctance to exercise, lethargy and depression, increased breathing effort and rate, coughing and occasional episodes of collapse or fainting. When your dog is examined by the vet, they may notice an increased heart rate, a heart murmur, pale gums and weak pulses. Other diagnostic tests such as blood tests, chest XRAYs, ECG and ultrasound scan of the heart may need to be performed. The other main condition that corvental D is often prescribed for is chronic bronchitis. This condition typically affects older dogs. Often, affected animals will cough and can show increased respiratory effort due to inflammed and constricted airways. Corvental for dogs causes the airways to dilate and relax (bronchodilation) and often leads to an immediate improvement in breathing.
How is Corvental D given?
Corvental D is available in capsule form. The capsules are coloured according to the strenth of the tablet. The following strengths are available:
What is Benefortin?
Benefortin are brownish oval tablets manufactured by Boehringer Ingleheim. Each Benefortin tablet contains either 2.5mg, 5mg or 20 mg benazepril hydrochloride.
How does Benefortin work?
After oral administration Benefortin is rapidly absorbed from the gastrointestinal tract and hydrolysed into benazeprilat a highly specific and potent inhibitor of angiotensin converting enzyme (ACE). Benazeprilat produces significant inhibition of plasma ACE activity for more than 24 hours after a single dose in both dogs and cats. Inhibition of ACE leads to a reduced conversion of inactive angiotensin I into angiotensin II and therefore reduction in the effects mediated by angiotensin II including vasoconstriction of both arteries and veins retention of sodium and water by the kidney and remodelling effects (including pathological cardiac hypertrophy and degenerative renal changes).
What is Benefortin used for?
Benefortin is indicated for the treatment of congestive heart failure in dogs and the treatment of chronic renal insufficiency in cats. In dogs with heart failure Benefortin lowers the blood pressure and volume loading effect on the heart. In cats with renal insufficiency Benefortin reduces the protein loss in urine and normalises the elevated glomerular capillary pressure and reduces systemic blood pressure. Reduction in glomerular hypertension retards the progression of kidney disease by inhibition of further damage to the kidneys. Benefortin has been shown to increase the appetite quality of life and the survival time of cats particularly in advanced disease.
How is Benefortin administered?
In both dogs and cats, Benefortin should be given orally once daily with or without food. The duration of treatment is unlimited
Benefortin is available in strengths of 2.5mg, 5mg and 20mg
A Veterinary Prescription is Required for Benefortin
Congestive heart failure in dogs is a chronic condition caused by heart disease, which often progresses very slowly and may take several years to become apparent. Congestive heart failure occurs when the heart of the dog has trouble pumping blood around the body, and may affect one side of the heart only, or both sides simultaneously.
A diagnosis of heart problems in your dog can of course be very worrying for the owner, however, while congestive heart failure cannot be cured or reversed, with veterinary treatment, many dogs can live happily for many years after diagnosis. In some cases, affected dogs can reach a grand old age in otherwise good health.
What causes congestive heart failure?
Getting to the root of the heart condition that ultimately leads to congestive heart failure is not always possible, and the fact that there is a problem at all may not become apparent for many years. There are a wide range of potential causes of congestive heart failure, including heart defects that are present from birth, a hereditary predisposition to heart problems, heartworm, infections, injuries, and simple old age.
Certain breeds of dog such as the Boxer tend to have an elevated occurrence rate of heart problems, and as such, may have a breed-specific predisposition to the problem.
The symptoms of congestive heart failure
It can be difficult to spot that there is something amiss with internal organs such as the heart, and so it is important to learn about the potential symptoms of heart disease in the dog and know how to spot them. Some of the potential symptoms of congestive heart failure include:
• Rapid, shallow breathing when at rest.
• Weakness and lethargy.
• A distended abdomen.
• A persistent, soft cough, particularly during exertion.
• Reluctance to exercise and play.
• Pacing, circling or otherwise taking a long time to settle down to sleep.
• Weight loss for no obvious reason.
• Swollen paws on all four legs.
• A grey or blueish colour to the gums.
Diagnosing congestive heart failure
If you spot any of the above symptoms or otherwise have cause for concern about your dog’s heart health, it is important to speak to your vet as soon as possible in order to get a firm diagnosis.
Your vet will look at your dog’s full clinical history, and talk to you in detail about your dog’s lifestyle, and the symptoms that you have noticed.
Your vet will then listen to your dog’s heart with a stethoscope, and may potentially also need to run some or all of the following tests:
• Blood and urine panels to rule out any other problems.
• Chest x-rays.
• EKG testing.
• Ultrasound examination.
• Heartworm antigen testing.
What can be done for congestive heart failure in the dog?
Once your vet has reached a diagnosis of congestive heart failure, what is done to treat and manage the condition will depend on exactly what your vet finds to be amiss with your dog’s heart, your dog’s age, and their general health and lifestyle. Some of the treatment options for the condition include:
• Medications such as Fortekor, Enacard or Benefortin to help the heart to function normally and regulate irregular heartbeats.
• Medications such as Corvental-D to help to support the heart, and resolve the fluid build-up in the lungs that can accompany the condition.
• Surgery to repair torn heart valves or to place a pacemaker to regulate the heartbeat.
• A special prescription diet such as Hill’s H/D to reduce fluid build-up in the body.
• A special exercise and weight management regime to help to keep your dog at a healthy weight while avoiding placing additional strain on the heart.
Managing the condition
Congestive heart failure cannot be reversed or cured, but by following your vet’s guidelines on the appropriate medications for your dog and any changes needed to their lifestyle, you should be able to keep your dog in otherwise good health, support their heart function, and prolong their healthy lifespan.
Obesity and weight problems can place additional strain on the heart and worsen the condition, and so it is important to keep your pet fit and healthy while also ensuring that they do not overexert themselves, placing further strain on their already compromised heart functions.
Once your dog has been diagnosed and treatment has begun, your vet will usually need to see your dog on a regular basis to monitor the progression of the condition and how effective their treatment protocol is proving to be, but generally, treatment for heart failure is performed on an outpatient basis at your local clinic.
Can congestive heart failure in the dog be prevented?
Heart problems that are present from birth or that have a hereditary element to them cannot be prevented, but in some cases, early surgical correction of known problems can repair the heart and keep later problems from developing.
Keeping your dog fit, healthy and at a suitable weight can all help to support lifelong heath too, as can ensuring that your dog stays up to date with their vaccinations, and is wormed regularly in accordance with your vet’s guidelines.
What are Cardalis Tablets for dogs?
Cardalis for Dogs is a new treatment for congestive heart failure and combines the diuretic Spironolactone with the ACE inhibitor Benazeapril. Cardalis is available in strengths of 2.5mg/20mg, 5mg/40mg and 10mg/80mg.Cardalis has been classified as a prescription-only medication or POM-V and as such is only available on prescription.
How do Cardalis Tablets work?
Cardalis tablets are a newly developed medication, indicated for dogs suffering with congestive heart failure. Cardalis contains a medicine called spironolactone. This drug is known as a diuretic ( a potassium-sparing diuretic) and can be helpful in reducing fluid build-up. However, it has been found that another, possibly more important property is that it spironolactone can help to prevent the scarring of heart tissue that can occur as the heart changes in structure (myocardial fibrosis), as often happens in cases of heart failure. Scarring or fibrosis can lead to an abnormal conduction of electrical impulses through the heart which may result in arrhythmias or abnormal heart rhythms. Benazepril, the other medicine present in cardalis, is known as an ACE-inhibitor (angiotensin converting enzyme inhibitor). This medicine is designed to reduce the re-absorption of fluid by the kidneys, a pathway that adds to the fluid accumulation in cases of congestive heart failure.
What are the symptoms of heart failure in dogs?
In cases of congestive heart failure, dogs accumulate fluid within the lung tissue (pulmonary oedema) or within body cavities (pleural effusion or ascites). Dogs generally either suffer from either pulmonary oedema (forward or left sided failure) or with ascites (fluid accumulating within the abdomen - known as right sided or backward failure). The type of fluid that accumulates will depend upon the underlying heart disease. General signs of heart failure include a reluctance to exercise, breathlessness, increased respiratory rate, pale gums and occasionally a moist cough or bloated abdomen. As the majority of these symptoms are fairly non-specific, it is essential that you seek diagnosis from a qualified veterinary surgeon.
A Veterinary Prescription is needed before we can dispense Cardalis
Treating congestive heart failure with Cardalis
Cardalis is a reasonably new product to reach the veterinary market, and has been approved for the treatment of congestive heart failure caused by chronic degenerative valve disease in dogs. Cardalis is manufactured by Ceva Animal Health, and contains the active ingredients benazepril hydrochloride and spironolactone.
Cardalis contains two active ingredients in balance for the optimal reduction of the harmful effects of canine heart failure, and scientific studies on the use of Cardalis in dogs have demonstrated significant improvements in both the life expectancy and quality of life of dogs treated with this medication. Cardalis can also be used in conjunction with other heart medications to increase its benefits, and is designed for lifelong use in affected dogs, with the minimum of potential side effects or secondary complications.
Why might my dog be prescribed Cardalis?
Cardalis may be prescribed if your dog is suffering from congestive heart failure caused by chronic degenerative valvular disease, with additional diuretic support, if appropriate.
How does Cardalis work?
Congestive heart failure can cause a multitude of systemic effects in the dog, including narrowing of the body’s blood vessels, fibrosis (scarring) of the walls of the blood vessels and thickening of the walls of the heart, all of which serve to raise your dog’s blood pressure and make the already damaged heart have to work harder to successfully circulate blood around the body and pump effectively.
Cardalis helps to open the body’s blood vessels, prevent thickening of the heart walls, and prevent fibrosis of the walls of the blood vessels, as well as reducing the stiffening of the heart muscle itself that is one of the signatures of congestive heart failure. Cardalis also reduces the accumulation of fluid within the body, which in turn, helps to lower blood pressure.
Some of the most common symptoms of congestive heart failure in dogs include exercise intolerance, loss of appetite and a persistent, soft cough that is not related to exertion or exercise; Cardalis helps to improve all of these symptoms, greatly improving your dog’s quality of life, and extending their viable lifespan in relatively good health and comfort.
Is Cardalis suitable for all dogs?
Cardalis should not be used in pregnant or lactating bitches, nor in dogs that are intended to be used for breeding later on. Cardalis is not suitable for use in dogs that are not fully grown, as it may inhibit normal growth and development in juvenile dogs.
Cardalis should not be used in conjunction with NSAIDS in dogs with chronic renal insufficiency, nor should it be prescribed to dogs diagnosed with hyponatraemia, hyperkalaemia, or hypoadrenocorticism.
Cardalis should not be prescribed for dogs that have proven to be hypersensitive to ACE inhibitors, nor dogs suffering from aortic or pulmonic stenosis, or cardiac output failure.
How is Cardalis administered?
Cardalis comes in the form of a beef-flavoured tablet for oral administration, and should be given once per day either just before a meal, or with food. Cardalis is a fixed combination product, containing two active ingredients, and as such, should only be given to dogs for whom the use of both active ingredients has been deemed necessary.
Cardalis should be administered in dosages calculated by the weight of the dog, at the rate of 0.25mg/kg of benazepril hydrochloride, and 2mg/kg of spironolactone.
Are there any side effects?
Cardalis is usually well tolerated by dogs, but as with any medications, some side effects may potentially occur.
Spironolactone, one of the two active ingredients in Cardalis, may cause reversible prostatic atrophy in entire (unneutered) male dogs, and Cardalis may potentially interact with various other medications that have been prescribed to your dog as well. When you are discussing your dog’s medications with your vet with a view to prescribing Cardalis, it is important that you tell your vet about any supplements or vitamins that you feed to your dog, as in some cases, these can interact with veterinary medications as well.
How can I get Cardalis for my dog?
Cardalis is a POM-V medication, which means that it can only be obtained with a veterinary prescription. Once your vet has approved the use of Cardalis for your dog and prescribed this medication, you can ask them to issue you with a prescription that can be used to purchase Cardalis from us.
Cardalis must be given daily as a lifelong medication in order to improve your dog’s quality of life and hopefully, extend their viable lifespan, and as such, you should not stop giving Cardalis to your dog nor change their dosage without first consulting with your vet.
You should also speak to your vet if you have any questions or concerns about your dog’s treatment with Cardalis, or any other issues relating to your dog’s ongoing health.
Carprodyl F Tablets are used for analgesia (pain relief) and reduction of inflammation caused by musculo-skeletal disorders and degenerative joint disease of the dog, such as arthritis
The active ingredient in Carprodyl F is Carprofen
A Veterinary Pet Prescription is required for Carprodyl F
Carprieve is a POM-V medication (Prescription only medicine) used for the reduction of inflammation and pain caused by musculoskeletal disorders and degenerative joint disease in Dogs.
Carprieve is also used as a follow-up to parenteral analgesia in the management of post-operative pain.
Carprieve dosage and administration - Oral administration: 4 mg Carprieve per kg bodyweight per day. An initial dose of 4 mg Carprieve per kg bodyweight per day given as a single daily dose. The analgesic effect from each dose persists for at least 12 hours. The daily dose may be reduced, subject to clinical response.
Duration of treatment with Carprieve will be dependant upon the response seen. Long term treatment should be under regular veterinary supervision. To extend analgesic and anti-inflammatory cover post-operatively parenteral pre-operative treatment with an injectable carprofen may be followed with Carprieve tablets at 4 mg/kg/day for 5 days. Do not exceed the stated dose for Carprieve.
A Veterinary Pet Prescription is required for Carprieve
Certifect spot on for dogs is used for the treatment and prevention of infestations in dogs by ticks and fleas.
Certifect contains the active ingredients Fipronil and Amitraz and is available in the following strengths: Certifect for Dogs 2-10 kg, Certifect for Dogs 10-20 kg, Certifect for Dogs 20-40 kg and Certifect for Dogs 40-60 kg
A Veterinary Pet Prescription is required for Certifect
Activyl is used in the treatment and prevention of flea infestation in cats and dogs and will also kill developing fleas in your pet's surroundings
Activyl contains the active ingredient indoxacarb and is available in the following strengths: Activyl spot-on solution for very small dogs, Activyl spot-on solution for small dogs, Activyl spot-on solution for medium dogs, Activyl spot-on solution for large dogs, Activyl spot-on solution for extra large dogs, Activyl spot-on solution for small cats and Activyl spot-on solution for large cats
A Veterinary Pet Prescription is required for Activyl
Canidryl is a "grilled meat" flavoured tablet used in the reduction of inflammation and pain caused by musculo-skeletal disorders and degenerative joint disease and as a follow up to parenteral analgesia in the management of post-operative pain for soft tissue surgery
Canidryl contains the active ingredient Carprofen and is available in the following strengths: 20mg Canidryl, 50mg Canidryl and 100mg Canidryl
A Veterinary Pet Prescription is required for Canidryl
Cimalgex Chewable Tablets for Dogs are for the treatment of pain and inflammation associated with osteoarthritis, and the management of peri-operative pain due to orthopaedic or soft tissue surgery, in dogs.
Cimalgex for dog arthritis
Cimalgex is a non-steroidal anti-inflammatory drug used in the treatment of canine arthritis, and in some cases, in the short-term management of post-operative pain. Cimalgex is distributed in the UK by Vetoquinol UK Ltd., and contains the active ingredient Cimicoxib.
Cimalgex is one of a range of NSAIDs that are widely used in veterinary practice as part of the treatment protocols to manage arthritis, and the effects that this can have upon the dog. Cimalgex has anti-inflammatory, analgesic and antipyretic properties, meaning that it helps to reduce the inflammation, pain and swelling that commonly accompany arthritic flare ups. Cimalgex can also be used on a short term basis to manage pain as part of recovery from surgical procedures.
Why might my dog be prescribed Cimalgex?
If your dog is diagnosed with arthritis, your vet will work with you to develop an inclusive care protocol to make your dog as comfortable as possible, improve their quality of life, and increase their range of movement. Dog arthritis causes pain, swelling and inflammation within the affected joints, all of which can make your dog stiff and uncomfortable, as well as causing chronic or acute pain that can make your dog reluctant to move or exercise. As dog arthritis is exacerbated by joint stiffness and lack of movement, this can serve to make the pain and other symptoms worse, and so the treatment and management of arthritis depends upon easing your dog's symptoms, and allowing them to lead as normal a life as possible. A combination of weight management, a suitable exercise routine, medications and possibly physical therapy are usually used for dogs with arthritis, and NSAIDs are an important part of helping to ease the pain and restore comfortable movement to your dog.
How does Cimalgex work?
Cimalgex contains the active ingredient Cimicoxib, which is a selective COX-2 inhibitor. Cox-2 is one of the body’s two coxib channels, along with Cox-1. The inflammation, and so, associated pain and discomfort of arthritis occur in the Cox-2 pathways, and so NSAIDS work by blocking these pathways off, to reduce the inflammation and associated pain. Some forms of NSAIDs are non-selective, and also block the Cox-1 pathways, which form compounds that help to protect the stomach and kidneys. This is part of the reason why some nonselective NSAIDs are poorly tolerated by some dogs, leading to gastrointestinal upsets.
As a selective Cox-2 inhibitor, Cimalgex helps to protect the kidneys and gastrointestinal tract, greatly reducing the chances of digestive side effects or damage to the kidneys as a result.
How is Cimalgex administered?
Cimalgex comes in tablet form, which is administered orally once per day. The tablets are palatable and so should be well received by most dogs, and are scored, so the tablets can be divided up into smaller doses if needed.Cimalgex can be given either with or without food, and is available in various different sizes to suit the needs of different dogs. For dogs treated with Cimalgex for osteoarthritis, usage should be reviewed after the initial six months. If the medication has proven to be effective during the initial six month period, treatment may be continued. However, monitoring of the functionality of the liver and kidneys is advised when Cimalgex is used long term, as the long term use of NSAIDs may potentially have a detrimental effect on healthy liver and kidney function.
Are there any side effects with Cimalgex?
As with all NSAIDs, the use of Cimalgex may potentially be accompanied by side effects in some dogs, although these are often restricted to the initial few days of treatment while your dog gets used to the medication. Speak to your vet if you have any concerns about your dog’s response to Cimalgex, or if their reactions to the medication are particularly pronounced. Some of the potential side effects and cautions on the usage of Cimalgex in dogs include:
• Potential risk of gastrointestinal upsets such as vomiting and diarrhoea.
• Lethargy and listlessness.
• Loss of appetite or refusing to eat.
• Weight loss.
• Long term use of Cimalgex may potentially impair kidney function, and so dogs prescribed Cimalgex long term should be monitored for any changes.
• Overdose with Cimalgex may cause acute kidney or stomach symptoms, which will require urgent veterinary attention.
• Special care should be taken when treating dogs with heart or liver diseases with Cimalgex.
How can I get Cimalgex for my dog?
Cimalgex is a POM-V medication, which means that it can only be purchased with a veterinary prescription. Your vet will discuss the various treatment options for your dog with you, and if they agree that Cimalgex is the best choice for your pet, they will issue you with a prescription for the product. You can use the prescription to order the medication from us.
Apoquel Tablets for dogs is a brand new medication used for the treatment of acute and chronic pruritus (itching) in dogs.
What are Apoquel Tablets?
Apoquel provides rapid relief of pruritus (itching) in dogs associated with allergic dermatitis and provides control of atopic dermatitis in dogs at least 12 months of age. Unlike common therapies such as steroids, cyclosporines or antihistamines, Apoquel is the only treatment specifically designed to go straight to the source of the itch.
Who are Apoquel Tablets for?
Apoquel is for dogs older than 12 months of age
Why use Apoquel Tablets?
- Apoquel reduces inflammation in the skin similar to glucocorticoids
- Apoquel reliefs itch caused by flea allergy, food allergy, contact allergy and atopic dermatitis in dogs.
- Apoquel targets the cause of the itch, it has minimal effect on other parts of the dog's body
How do Apoquel Tablets work?
- Apoquel starts to relieve the itch within 4 hours, comparable to steroids.
- Apoquel effectively controls the itch within 24 hours
- Apoquel relieves itch in the long term.
Active ingredient: Apoquel tablets contain 3.6 mg, 5.4 mg, or 16 mg of oclacitinib as oclacitinib maleate per tablet. Each tablet is scored and marked with AQ and either an S, M, or L that correspond to the different tablet strengths on both sides.
What are the side effects of Apoquel Tablets?
In most cases, diarrhea, vomiting, anorexia, and lethargy spontaneously resolved with continued dosing.
What special precautions are there?
Apoquel is not for use in dogs with serious infections. Apoquel may increase susceptibility to infection, including demodicosis, and exacerbate neoplastic conditions. Apoquel is not for use in breeding dogs, or pregnant or lactating bitches. The use of Apoquel has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents. Dogs receiving Apoquel should be monitored for the development of infections, including demodicosis, and neoplasia.
A Veterinary Pet Prescription is required for Apoquel
Apoquel is a newly approved product designed to ease the symptoms of pruritic conditions including allergic dermatitis and atopic dermatitis in dogs.
Skin conditions and chronic dermatitis may not be life threatening conditions, but they can make your dog really itchy and uncomfortable, which in turn can lead to your dog scratching themselves to distraction in order to gain some relief from their discomfort. Scratching, obsessive licking and biting at particularly irritating areas of the skin can soon exacerbate the problem, leading to redness and inflammation, as well as bald patches and sore spots that can soon become a host to bacterial and viral infections, creating a vicious circle of scratching, further irritation, and additional damage to the skin.
What is Apoquel?
Apoquel is a POM-V medication, meaning that it can only be sold with a veterinary prescription, and it is sold in tablet form for oral administration.
The active ingredient in Apoquel is Oclacitinib, which is a Janus kinase (JAK) inhibitor. This means that the medication will inhibit the function of certain cytokines, a form of chemical switching gears that control various immune-mediated reactions. When your dog suffers from itchy dermatitis, the cytokines that your dog’s immune system generates due to the allergenic trigger can lead to serious itching or pruritus of the skin, exacerbating the body’s immune responses. Oclacitinib helps to mute or inhibit the response of this specific immune reaction, targeting cytokines that cause the allergenic response and proinflammatory elements of the reaction.
This in turn helps to reduce the itching and irritation that such conditions trigger across the body of your dog, making them more comfortable and less likely to scratch constantly.
How is Apoquel used?
Apoquel is given in tablet form, which can be administered either with or without food. The initial dose for dogs prescribed Apoquel is 0.4-0.6mg of Oclacitinib per kg of bodyweight given twice daily for the first fourteen days.
After the initial two week period, assuming that Apoquel has proven suitable for your dog, a maintenance dose of 0.4-0.6mg/kg of bodyweight is recommended, given once per day.
Treatment and maintenance of the efficacy of Apoquel should be monitored by your veterinary surgeon, and regularly reviewed.
Does Apoquel cure pruritic dermatitis?
Apoquel is designed to soothe and treat one of the most problematic symptoms of pruritic dermatitis, rather than to treat or cure any of the various underlying causes of the condition.
For dogs suffering from allergic dermatitis, establishing the trigger or triggers of the condition and limiting exposure to them is the best way of resolving the condition permanently, which may require a range of tests and exposure trials to be arranged by your veterinary surgeon.
In the case of dermatitis caused or complicated by external factors such as a hypersensitivity to fleas, demodectic mange or other parasites, treating and resolving the underlying condition is the best form of resolving the issue for the long term.
Is Apoquel suitable for all dogs?
Apoquel is suitable for the vast majority of dogs suffering from allergic dermatitis or other pruritic skin conditions, but is unsuitable for dogs that have proven to be hypersensitive to the active ingredient, Oclacitinib. Apoquel may also prove unsuitable for dogs suffering from immune-suppressant conditions such as hyperadrenocorticism or progressive malignant neoplasia, or any other conditions that serve to supress the immune system.
To date, clinical trials on pregnant and lactating bitches have yet to be undertaken, and so Apoquel is not recommended for use during gestation or nursing. Apoquel is suitable for adult dogs only, and should not be prescribed for dogs under twelve months of age, or for dogs with a bodyweight of less than 3kg.
Because Apoquel supresses some of the body’s Immune responses, long-term use of Apoquel may increase the risk of susceptibility to infections, and the development of neoplastic tumour formations. Dogs undergoing long-term treatment with Apoquel should have their blood count and serum biochemistry monitored periodically, in order to ensure that their wider immune system does not become affected.
Apoquel is generally a well-tolerated medication with few potential side effects, however, as with any medication, Apoquel may prove unsuitable for some dogs. Often, minor side effects of Apoquel will go away within a few days of beginning treatment with the medication, but any problems that become acute or remain after the initial two week period may mean that Apoquel is unsuitable for your dog, and may need to be discontinued.
Some of the potential side effects of the medication can include vomiting and/or diarrhoea, loss of appetite, increased thirst, and lethargy, although these effects only present within a very small number of dogs treated with Apoquel, and generally resolve themselves promptly and without becoming acute.
Speak to your vet if you have any concerns about the use of Apoquel, or if you wish to stop treatment.