How Galliprant Works

Galliprant works by blocking the EP4 receptor, which is primarily responsible for pain and inflammation associated with osteoarthritis. Unlike traditional NSAIDs, which inhibit cyclooxygenase (COX) enzymes, Galliprant specifically targets this receptor without affecting other prostaglandins that support normal bodily functions.

This selective action reduces the risk of gastrointestinal, kidney, and liver side effects that are commonly associated with other NSAIDs. Because it works at the root of inflammation rather than through broad suppression, Galliprant provides effective pain relief while maintaining overall health and well-being.

VETERINARY PRESCRIPTION REQUIRED

20mg Galliprant for Dogs

Galliprant may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Galliprant if you have or are in the process of arranging such a prescription. See information bar for further details.

Osteoarthritis in Dogs

Osteoarthritis (OA) is a degenerative joint disease that affects millions of dogs. It occurs when the cartilage that cushions the joints deteriorates over time, leading to pain, stiffness, and inflammation. The condition is progressive, meaning it worsens with age, and there is no cure. However, effective management can improve a dog’s comfort and mobility.

Causes of Osteoarthritis

Several factors contribute to the development of osteoarthritis in dogs. The most common include:

Age: Older dogs are more prone to joint degeneration.
Breed: Large and giant breeds, such as Labradors, Golden Retrievers, and German Shepherds, are at higher risk.
Genetics: Some dogs have a genetic predisposition to joint conditions.
Obesity: Excess weight puts additional stress on the joints, accelerating cartilage wear.
Joint Abnormalities: Conditions like hip or elbow dysplasia increase the likelihood of developing osteoarthritis.
Previous Injuries: Fractures, ligament tears, or joint trauma can lead to early-onset arthritis.

Signs of Osteoarthritis

The symptoms of osteoarthritis can vary in severity, but common signs include:

Stiffness, especially after resting
Reluctance to exercise, jump, or climb stairs
Lameness or limping
Swelling around the joints
Difficulty rising from a lying position
Changes in behaviour, such as irritability or withdrawal

Dogs often hide their discomfort, so subtle behavioural changes should be monitored closely. Early intervention can help slow the disease’s progression and improve long-term outcomes.

Managing Osteoarthritis with Galliprant

Galliprant helps manage osteoarthritis by reducing inflammation and relieving pain, making daily activities more comfortable for affected dogs. It is often used as part of a comprehensive treatment plan that may include:

Weight Management: Maintaining a healthy weight reduces stress on joints.
Exercise Modification: Regular, low-impact activities such as swimming or short walks help maintain muscle strength.
Joint Supplements: Products containing glucosamine, chondroitin, or omega-3 fatty acids support joint health.
Physical Therapy: Physiotherapy and hydrotherapy can improve mobility and reduce stiffness.

Galliprant is particularly beneficial for long-term use due to its selective action. It allows dogs to continue their daily activities with minimal risk of organ-related side effects.

Dosage and Administration

Galliprant is available in various strengths, including 20mg, to suit different dog sizes. The dosage is based on body weight and should always be prescribed by a veterinarian.

The typical dose is 2mg per kg of body weight once daily. Tablets should be given whole and can be administered with or without food. Owners should follow the vet’s instructions carefully and not adjust the dosage without professional advice.

Safety and Precautions

Galliprant has been shown to be safe for long-term use, but certain precautions should be taken:

Not for Use in Cats or Humans: Galliprant is formulated specifically for dogs and should never be given to other animals or people.
Puppies Under 9 Months: The safety of Galliprant in very young dogs has not been established.
Dogs with Severe Kidney or Liver Disease: Veterinary guidance is essential before use.
Pregnant or Breeding Dogs: Not recommended for use in breeding, pregnant, or lactating dogs.
Interaction with Other Medications: Owners should inform their vet of any other medications their dog is taking, including other NSAIDs or corticosteroids.

Possible side effects are mild in most cases and may include vomiting, diarrhoea, or loss of appetite. If these symptoms persist or worsen, veterinary advice should be sought immediately.

Storage and Handling

Galliprant should be stored in its original packaging at room temperature, away from moisture and direct sunlight. Tablets should be kept out of reach of children and other pets. If a dose is missed, it should be given as soon as possible, unless it is close to the next scheduled dose. In such cases, the missed dose should be skipped to avoid overdosing.

Galliprant is an essential medication for managing osteoarthritis in dogs, providing effective pain relief while minimising common side effects associated with traditional NSAIDs. Always consult a veterinarian before starting treatment to ensure the correct dosage and suitability for your pet.