Malaseb Shampoo is used for the treatment and control of seborrhoeic dermatitis associated with Malassezia pachydermatis andStaphylococcus intermedius in dogs. Malaseb Shampoo is used as an aid in the treatment of ringworm due to Microsporum canis in the cat in conjunction with griseofulvin.
Malaseb contains the active ingredient Chlorhexidine digluconate and is available in the following strengths: 250ml Malaseb Shampoo
A Veterinary Pet Prescription is required for Malaseb Shampoo
Meloxidyl Oral is a non-steroidal anti-inflammatory drug (NSAID) for use in the alleviation of inflammation and pain in acute and chronic musculo-skeletal disorders in dogs. Vet Prescription Required
Meloxidyl contains the active ingredient meloxicam and is available in the following strengths: 10ml Meloxidyl, 32ml Meloxidyl and 100ml Meloxidyl
A Veterinary Pet Prescription is required for Meloxidyl
Marbocyl P is indicated in the treatment of skin and soft tissue infections in Cats and Dogs
Marbocyl P contains the active ingredient and is available in the following strengths: 5mg Marbocyl, 20mg Marbocyl and 80mg Marbocyl
A Veterinary Pet Prescription is required for Marbocyl P
Metacam (or meloxicam) is a pet prescription medication for dogs that can be prescribed by your vet for the treatment of painful, inflammatory conditions such as arthritis or soft tissue injuries in dogs.
Metacam is a non-steroidal anti-inflammatory drug (NSAID). Metacam works by inhibiting an enzyme known as cyclooxygenase (particularly cyclooxygenase-2) that is responsible for prostaglandin synthesis. Because osteoarthritis is an inflammatory condition, Metacam and other NSAIDs are highly effective at controlling this form of pain and often bring much needed relief to a stiff and sore animal.
Many owners report that their pet has a 'new lease of life' following Metacam therapy. Metacam is most widely available in liquid form that is usually very palatable, and its taste is thought to be similar to that of honey!
Other formulations of Metacam include tablets and a liquid for injection. Osteoarthritis is a painful condition that can affect an animal's joints. Arthritis is often seen in older animals due to the aging process, although some younger pets may develop this condition as a consequence of other illnesses such as hip dysplasia or cruciate disease in dogs. Arthritic pain is also becoming increasingly diagnosed in cats, as we are progressively more able to identify symptoms of pain in this species.
If you suspect that your pet may be suffering from joint disease, it is important that you visit your Vet who may need to perform further tests to confirm the diagnosis. It may be necessary for your vet to take blood from your pet to ensure that any metacam prescription is appropriate in the first instance, and that it is not having a detrimental effect upon internal organs in the longer term.
Metacam oral suspension for cats is available in 15ml and Metacam oral suspension for dogs is available in 32ml, 100ml and 180ml bottle
A Veterinary Pet Prescription is required before we can dispense Metacam
Metacam for dog arthritis
Metacam is an oral medication that is also sometimes known as Meloxicam, and which is distributed in the UK by Boehringer Ingelheim Ltd. Metacam can be prescribed for both dogs and cats, and is often used for the treatment and management of the symptoms of canine arthritis.
Metacam is one of the class of non-steroidal anti-inflammatory drugs or NSAIDs, which work to reduce both pain and fever. Metacam, or Meloxicam as it is known generically, is derived from oxicam, which falls within the enolic acid group of NSAIDs.
Why might my dog be prescribed Metacam?
If your dog is diagnosed with arthritis, they will likely display a range of symptoms as a result of the joint swelling and stiffness that accompany the condition. Common symptoms of canine arthritis include pain in the affected joints, stiffness and difficulty moving freely, and a reluctance to get up and move due to the pain that can accompany this.
As movement is important in reducing the pain of arthritis, this can soon turn into something of a vicious circle, where the pain of the condition inhibits movement, which in turn, makes the pain worse. In order to keep your dog mobile and reduce the pain that they experience as part of their condition, your vet will consider a range of options to treat their condition on an ongoing basis.
This may include physical therapies such as hydrotherapy and massage, as well as the prescription of medications that can reduce joint pain and inflammation, and help to keep your dog active. If your dog is overweight, your vet will also work with you to manage their food intake in order to get them back into shape, as obesity too can exacerbate the pain and other symptoms of arthritis.
When it comes to medications for canine arthritis, NSAIDs are the usual choice. NSAIDs work to reduce the swelling and heat in the affected joints, and so, the pain associated with it. Metacam is one of the most popular NSAIDs used for the treatment and management of arthritis in dogs, and is usually well tolerated with less potential for side effects than other options.
How does Metacam work?
Metacam is just one of many different NSAIDs, all of which work slightly differently, which means that there is no one size fits all best choice for every dog. However, Metacam is one of the most widely used NSAIDs for the treatment of arthritis in dogs, and one that consistently achieves good results with fewer side effects than most alternatives.
Metacam is a medication from the coxib group, and selectively inhibits COX-2, leading to a reduction in the inflammation and pain that accompany canine arthritis. Metacam works by blocking the cyclo-oxygenase enzyme that produces prostaglandins, which trigger fever, inflammation and pain in the joints.
Metacam is different from many NSAIDs as it preferentially inhibits COX-2 rather than Cox-1, which serves to reduce the side effects of the medication, such as stomach and gastrointestinal upsets.
How is Metacam administered?
Metacam may be given by your vet in the form of an injection in the first instance, but for usage at home, Metacam is administered orally. Metacam can be purchased as either a chewable tablet or an oral suspension, which can be administered directly by mouth, or added to the dog’s food if they will accept it.
Are there any side effects?
All NSAIDs come with the potential risk of side effects for dogs, particularly with long term usage. Dosage rates should be kept as low as possible while still producing the desired results, and for some dogs, Metacam usage can be suspended at times when the dog is not suffering from a particularly acute arthritic flare up.
Side effects are more likely to occur in older dogs, or those with compromised immune systems or that are otherwise not in good general health.
The most common side effects of Metacam for dogs are loss of appetite, and stomach upsets including nausea, vomiting and diarrhoea. While these reactions are often short term and minor, you should speak to your vet if they occur, as they may necessitate renal parameter testing and liver enzyme testing to ensure that your dog’s major functions are not compromised.
NSAIDs such as Metacam should not be used in dogs with borderline kidney function, nor in dogs that are dehydrated.
In rare cases, Metacam can cause idiosyncratic liver toxicity in treated dogs, which is not related to the dosage rate or any other measurable parameters. While a reaction of this type is extremely unlikely, it is important that the owners of all dogs prescribed Metacam are aware of the potential risk.
How can I get Metacam for my dog?
Metacam is a POM-V medication, and as such, requires a veterinary prescription in order to be sold.
Once you have a veterinary prescription for your dog, you can use your prescription to order online from us.
Microbex Shampoo is for use in dogs for the treatment of Malassezia pachydermatis surface proliferation and the control of associated clinical signs
Microbex Shampoo contains the active ingredient chlorhexidine digluconate and is available in the following strengths: 200ml Microbex Shampoo
A Veterinary Pet Prescription is required for Microbex Shampoo
Milbemax is an oral broad-spectrum worming tablet for the treatment of mixed infections with roundworms, hookworms, whipworms and tapeworms, reduction in the level of infection of lungworms and the prevention of heartworm disease in dogs if concomitant treatment against cestodes is indicated.
Milbemax is a highly effective broad-spectrum treatment. With its fast and direct gastrointestinal action, Milbemax effectively removes worm burden in infected dogs. It is effective against adult cestodes and nematodes. Milbemax Chewable tablets for dogs are uniquely formulated with Easychew Technology to make worming more of a treat.
The soft chewable tablets are chicken flavoured and over 94% of dogs accept them straight from the hand. Because Milbemax is an oral treatment it ensures that the right dose is delivered straight to the intestinal tract, making it a direct and mess-free option for owners and pets.
Milbemax contains the active ingredients Milbemycin oxime and Praziquantel
A Veterinary Pet Prescription is required for Milbemax
Nelio tablets are indicated for the treatment of heart failure in dogs and chronic renal insufficiency in cats. The active ingredient of Nelio is benazepril. Nelio is available as 5mg Nelio Tablets and 20mg Nelio Tablets
Nelio reduces the constriction of both arteries and veins (and so lowers blood pressure and improves kidney function), reduces the retention of sodium and water by the kidney (something that contributes to the signs of heart failure) and helps to prevent some of the changes that occur to the anatomy of the heart in cases of heart failure. In dogs with heart failure, Nelio reduces the blood pressure and volume load on the heart. Nelio produces an extension of the life span and also improves clinical signs, notably reduction in coughing, and improvement to the quality of life. In cats with chronic renal insufficiency Nelio reduces the protein loss in urine and reduces systemic and intraglomerular blood pressure.
Nelio increases the appetite, quality of life and survival time of the cats, particularly in advanced disease. Nelio should be given orally once daily, with or without food. The duration of treatment is unlimited. The dose of Nelio may be doubled, still administered once daily, if judged clinically necessary and advised by your veterinary surgeon.
Nelio is only available with a written Veterinary Prescription
Nisamox Tablets are an antibiotic used for treatment of the certain bacterial infections
Nisamox contains the active ingredients Amoxicillin and Clavulanic acid and is available in the following strengths: 50mg Nisamox, 250mg Nisamox and 500mg Nisamox
A Veterinary Pet Prescription is required for Nisamox
Noroclav tablets contain the antibiotics amoxycillin and clavulanic acid, which are used to treat wide range of bacterial infections in dogs, including infections of the skin, urinary and respiratory tract and digestive system.
Noroclav is available in the following strengths: 50mg Noroclav, 250mg Noroclav and 500mg Noroclav
A Veterinary Pet Prescription is required for Noroclav
Onsior is a new fast-acting pain reliever which concentrates at the site of inflammation. Onsior is available as both an injectable solution and flavoured tablets. Onsior is the first and only coxib NSAID (non-steroidal anti-inflammatory drug) for the relief of pain and inflammation in both cats and dogs. Onsior targets the pain-causing COX-2 enzymes while sparing the protective actions of COX-1 and is the only coxib licensed for cats as well as dogs. Tissue selectivity is a further benefit of Onsior. The drug travels rapidly through the bloodstream to the site of injury or irritation. It then concentrates at the point of inflammation, while exiting the bloodstream very quickly. Dosed once daily, Onsior has an excellent safety profile and fits different administration routes with pain and inflammatory indications Onsior Flavoured tablets, for pain and inflammation related to chronic osteoarthritis in dogs or acute pain and inflammation associated with musculoskeletal disorders in cats Onsior injectable solution for surgery (soft tissue in cats and soft tissue or orthopaedic surgery in dogs)
Onsior contains the active ingredient Robenacoxib and is available in the following strengths: 5mg Onsior, 10mg Onsior, 20mg Onsior and 40mg Onsior
A Veterinary Pet Prescription is required for Onsior
What is Optimmune?
Optimmune eye ointment for dogs contains Cyclosporin A as its active ingredient. Optimmune is a prescription only medicine, usually prescribed for dogs that are suffering from a condition known as dry eye or keratoconjunctivitis sicca.?
How does Optimmune work?
Optimmune works by suppressing the ability of the immune system to function within the eye. This specifically reduces the function of T lymphocytes and the immune-mediated destruction of the tear gland.
What is Optimmune used for?
Optimmune is used for the treatment of chronic, recurrent conjunctivitis resulting from autoimmune disease of the eye. Optimmune is indicated for the therapeutic treatment of Keratoconjunctivitis sicca (KCS, ‘dry eye’) and chronic superficial keratitis (‘pannus’) in the dog. Optimmune be used to augment topical corticosteroids or as a substitute for corticosteroids when these are contraindicated by corneal ulceration.
What is Dry Eye or Keratoconjunctivitis Sicca (KCS)?
Dry eye or KCS occurs when dogs are unable to produce the watery, aqueous layer that makes up part of the tear film. This results in the cornea (at the front of the eye) becoming dry and inflamed and can even lead to the development of corneal ulcers. Often, animals that are suffering from dry eye will have dull, red eyes with a thick, mucous discharge forming at the corner of the eye. In severe cases, if left untreated, affected animals may lose some or all of their vision. Dry eye is thought to affect 1 in every 22 dogs in the UK. There are several different causes of dry eye, however the most common cause is thought to be immune-mediated destruction of the tear gland. This occurs when your dog's immune system changes and starts to recognise the tear-producing cells as being foreign. Optimmune contains cyclosporin (an immunosuppressive drug) that reduces the immune-mediated destruction of tear glands, allowing your dog to naturally produce the aqueous component of the tear film. This is essential in keeping the eye lubricated and protected from infection and inflammation.
Which Breeds Are Most Susceptible to Dry Eye?
Any breed of dog can develop dry eye, however the following breeds seem more susceptible than others: • English Cocker Spaniel • West Highland White Terrier • Cavalier King Charles Spaniel • Shih-Tzu
How Should Optimmune be used?
You should always follow the advice of your Vet when using Optimmune. Unfortunately, dry eye is often a life-long condition that cannot be cured and requires continual medication. It is important to continue with optimmune unless told otherwise by your vet, even if your dog's eyes appear to have improved. Generally, most dogs are initially started on twice daily treatment and around 5mm of optimmune paste (about the size of a grain of rice) is required. Gloves should be worn when handling this product. Increased tear production is expected within 10 days of treatment, although maximal levels may not be reached until 6 weeks following treatment. Your Vet may also prescribe other drugs such as steroids for their anti-inflammatory effects, and antibiotics to clear up infections. Artificial tears may also be recommended to make the eye feel more comfortable. None of these treatments will however, treat the underlying cause which is the destruction of tear glands by the immune system. Optimmune is the only product that can achieve this goal.
A Veterinary Prescription is Required for Optimmune
Dry eye in dogs (Keratoconjunctivitis sicca)
The condition commonly known as dry eye in dogs is more properly known by the veterinary term “Keratoconjunctivitis sicca” or KCS, and occurs when the eyes of the dog do not produce enough natural lubrication in the form of tears. Left untreated, dry eye can lead to permanent damage and scarring to the tissue of the eyes, and even potentially blindness.
In this article, we will look at dry eye in dogs in more detail, including why it occurs, and what can be done to manage the condition and preserve your dog’s vision.
Lubrication is vital to ensure the healthy functioning of your dog’s eyes, and the eyes should always appear to be clear, moist and bright. The tear ducts, a type of glands at the sides of the eyes, are responsible for producing sufficient lubrication to keep the eyes healthy, and this lubrication is distributed across the surface of the eyes when your dog blinks. Blinking helps to spread a protective layer of lubrication over the eyeball, which keeps the inside of the eyelid and the eyeball itself healthy.
Lubrication also helps to wash foreign bodies out of the eyes, provide essential nutrients to the cornea, and help to prevent bacterial infections of the eyes.
In dogs that suffer from dry eye or KCS, the tear ducts do not produce enough lubrication on their own to efficiently keep the eyes moist and healthy, which can lead to a range of problems. While the reasons for dry eye are not fully understood, it is thought that dry eye is an autoimmune condition, in which the dog’s own body treats the tear ducts as an invader and attempts to limit or destroy their normal functionality.
Exactly how severe the presentation of dry eye is in any given dog will vary, but if left untreated, dry eye can lead to progressive damage to the tear ducts themselves, to the point that they may ultimately stop producing lubrication entirely.
What are the symptoms of dry eye in dogs?
As is the case with many canine conditions, the symptoms of dry eye are not always uniform from dog to dog, and the presentation of the condition and its severity can vary. Some of the signs of dry eye to keep a lookout for include:
It is important to note that during the early stages of the development of the condition, while any or all of the above symptoms may be observed, the eyes may not actually appear to be particularly dry.
Diagnosing dry eye in dogs
In order to get a formal diagnosis of dry eye, you will need to take your dog along to the vet for them to perform a Schirmer tear test, which involves using a strip of absorbent paper to measure the amount of fluid gathered under the lower eyelid of the dog in one minute. From this, your vet will be able to determine the volume of tears that your dog produces.
A fluid level of 20 or above indicates normal tear production, while a level of 15 or lower shows a potential shortage of tears. A level of 10 or below indicates insufficient production of lubrication from the tear ducts, and so, a definitive diagnosis of dry eye.
How is dry eye treated?
Dry eye is a lifelong condition that cannot usually be completely corrected, and so treatment of dry eye in the dog depends on ongoing medication or treatments to generate additional tear production, or lubricate the eyes.
Some of the treatment options for a dog with dry eye include:
Ovarid is a potent progestagen with marked anti-oestrogenic properties. It is recommended for administration by the oral route in bitches for the postponement or prevention of oestrus and the treatment of hypersexuality which may be manifest as undesirable behaviour in male dogs. In cats it is recommended for prevention or postponement of oestrus and the treatment of miliary dermatitis and eosinophilic granulomata.
Ovarid contains the active ingredient Megestrol acetate and is available in the following strengths: 5mg Ovarid for Cats and 20mg Ovarid for Dogs
A Veterinary Pet Prescription is required for Ovarid
Ovarid for cats
Ovarid is an oral medication that is designed to postpone or prevent your female cat coming into oestrus (heat) and therefore controlling the ability of the unspayed cat to reproduce. Ovarid can also be used in the treatment of miliary dermatitis and eosinophilic granuloma in cats too.
In this article, we will examine Ovarid in more detail, and how it can be used in cats.
What is Ovarid?
Ovarid is progestagen (synthetic hormone) agent comprised of magestrol acetate, with has potent anti-oestrogen properties, which means that it can postpone or delay your cat coming into heat, and so, being able to mate and breed.
Ovarid comes in tablet form in strengths of 5mg and 20mg, and is administered orally.
What does Ovarid do?
Ovarid is mainly prescribed to delay or prevent your cat from coming into heat, both preventing them from breeding and removing the urge to breed, which can itself manifest as a range of undesirable behaviours, as well as hormonal signals that can attract entire male cats. Ovarid can be used selectively to manage the heat cycles of the unspayed female cat as a form of contraceptive, and to mute the undesirable behaviours that can accompany sexual behaviours including calling and roaming.
Unspayed female cats can come into heat as often as every three-four weeks, making the management of female cats that are not intended for planned mating challenging.
Ovarid has also proven very successful in treating miliary eczema in cats, a type of skin disorder that can lead to crusty lesions across the skin, which may be inflamed and irritated. Ovarid can also be beneficial in the treatment of eosinophilic granulomas or cutaneous skin rashes in cats, which again, can be sore and irritable as well as unsightly.
When is Ovarid indicated?
The most effective and widely recommended method of preventing reproduction in the female cat is surgical spaying, which is a permanent procedure that removes both the urge and the ability to reproduce, as well as reducing the risk of cancers and other conditions of the reproductive system in later life.
However, for some cats, spaying is not an option, due to problems such as a hypersensitivity to the anaesthetic compounds used in surgery, or because or other health conditions that elevate the risk factors associated with the surgery.
Some female cats are of course left unspayed deliberately in order to enable breeding, particularly in the case of good quality pedigree cats from desirable bloodlines. However, as mentioned, unspayed female cats can come into heat every few weeks, and of course, it is not appropriate or desirable that the cat should conceive every time that they come into heat. Ovarid can help to temporarily remove the urge and ability to breed, allowing for planned matings and designated recovery periods for the breeding queen, without the associated problems that accompany a regular heat cycle.
In cats of either sex, spayed or unspayed, Ovarid may also be indicated in the case of miliary eczema or eosinophilic granuloma flare-ups, proving highly effective in treating both types of skin disorders in cats.
Is Ovarid suitable for all cats?
Ovarid is a synthetic hormone, and as such, should be administered with care, as it produces a systemic effect on the body of the cat. Ovarid should not be prescribed for diabetic cats nor cats that have yet to undergo their first heat cycle, and care should be taken when treating elderly cats with Ovarid.
Using Ovarid to prevent or postpone the heat cycle is not an exact science, and no guarantee can be provided regarding how long the dosage will prove effective for, or how soon normal heat cycles will return. Some disruption in the normal heat cycle of the unspayed cat is normal after the use of Ovarid, and this can make planned breeding after usage more complicated.
Ovarid is generally well tolerated and not apt to produce wide ranging or acute side effects in cats, but in rare cases, weight gain, increased appetite and lethargy may accompany the use of the medication.
Ovarid may in rare cases lead to mammary hypertrophy in cats that are prescribed Ovarid long term for miliary eczema, although this condition may go into regression upon cessation of the medication.
How can I get Ovarid for my cat?
Ovarid is a POM-V medication, meaning that it can only be prescribed with a veterinary prescription. Your vet will need to examine your cat and find out the reasons behind why you wish to use Ovarid, before approving or recommending Ovarid for your cat to prevent oestrus or to treat miliary eczema or eosinophilic granulomas. Your cat’s treatment protocol should also be reviewed on a regular basis to ensure that Ovarid is proving effective for your cat, and remains the best course of treatment for them.
Once your vet has approved the use of Ovarid, you can ask your vet for a veterinary prescription to purchase the medication from us.
Oxycare is an antibiotic for the treatment of dogs with bacterial infections sensitive to tetracycline therapy. Soft-tissue infections caused by Staphylococcus aureus or Streptococcus spp. have been shown to be highly sensitive to Oxycare. Respiratory infections caused by Bordetella bronchiseptica are also commonly sensitive.
Oxycare contains the active ingredient Oxytetracycline Dihydrate and is available in the following strengths: 50mg Oxycare, 100mg Oxycare and 250mg Oxycare
A Veterinary Pet Prescription is required for Oxycare
Prednisolone is used as an anti-inflammatory and anti-allergic agent for use in cats and dogs
Prednisolone contains the active ingredient 'Prednisolone' and is available in the following strengths: 1mg Prednisolone and 5mg Prednisolone
A Veterinary Pet Prescription is required for Prednisolone
Predno-Leucotropin is used for the treatment of osteoarthritis in dogs
PLT Tablets contains the active ingredients Cinchophen and Prednisolone
A Veterinary Pet Prescription is required for PLT Tablets
Heart failure is a condition which is seen relatively frequently in dogs. Prilactone is available on prescription and is often used alongside other heart medicaions in dogs to control some of the symptoms of congestive heart failure. These symptoms include a tendency towards reduced exercise tolerance and increased tiredness, increased panting and the effort required to breath is often exhagerated. Some dogs may also cough or show enlargement of the tummy. Affected dogs may also begin to lose weight. Prilactone is used in combination with standard therapy (including diuretic support, where necessary) for the treatment of congestive heart failure caused by valvular regurgitation in dogs. Prilactone is known as a potassium-sparing diuretic and is sometimes used in combination with other diuretics suct as frusemide if there is concern regarding low potassium levels. However, another important reason for using prilactone is for the beneficial effects that it has upon cardiac remodelling. As the heart tissue becomes diseased, (e.g through problems with the valves), the cells making up the heart muscle (myocardium) can undergo changes that make them less capable of performing their normal function - this change is known as fibrosis. Prilactone reduces fibrosis and has been shown to improve and extend the quality of life of dogs with heart failure that is caused by mitral valve disease.
Prilactone contains the active ingredient Spironolactone and is available in the following strengths: 10mg Prilactone, 40mg Prilactone and 80mg Prilactone
A Veterinary Pet Prescription is required for Prilactone
Propalin Syrup is used for the treatment of urinary incontinence associated with urethral sphincter incompetence in the bitch.
Urinary incontinence is an involuntary loss of urine that can occur in the dog at any age and in either sex. It is particularly common in the elderly bitch. You may have been finding patches of urine where your dog has been lying, or in other places around the house. This ‘leaking’ is not under conscious control and requires treatment, not punishment
There are many factors which may contribute to urinary incontinence, including anatomy, being spayed, breed, age, size or weight. Urine is contained within the bladder and is prevented from leaking out by the urethral sphincter, which largely consists of muscle. The activity of the muscle is regulated by nerves which have both conscious and unconscious control. The sphincter normally remains closed until the animal consciously decides to urinate. However, if the sphincter is lax, as occurs in incontinence, urine will leak out. Although your dog will still be able to urinate at will, there may be a leakage of urine over which she has no control. This may, understandably, distress both you and your pet, as well as smelling unpleasant and possibly leading to further problems, such as scalding or infection around the rear end.
Propalin Syrup contains phenylpropanolamine hydrochloride. Phenylpropanolamine acts to increase the tone in muscles that make up the urethral sphincter. It does this by mimicking the action of the nerves which are responsible for the tone of the muscles. The increase in tone results in a tightening of the urethra so preventing leakage of urine.
A Veterinary Pet Prescription is Required for Propalin
Program Plus is indicated for the prevention of fleas and/or treatment of adult stages of gastrointestinal nematodes such as hookworms, roundworms and whipworms in dogs.
Program Plus contains the active ingredients milbemycin oxime and lufenuron and is available in four different sizes.
A Veterinary Pet Prescription is required for Program Plus
Posatex Treatment of acute otitis externa and acute exacerbations of recurrent otitis externa, associated with bacteria susceptible to orbifloxacin and fungi susceptible to posaconazole, in particular Malassezia pachydermatis
Posatex contains the active ingredients orbifloxacin, mometasone furoate and posaconazole and is available in the following sizes: 17.5ml Posatex and 35ml Posatex
A Veterinary Pet Prescription is required for Posatex
What is Prascend for horses?
Prascend Tablets contain 1mg Pergolide. 1mg Prascend is used as a treatment for cushings disease in horses. A small benign tumour in the pituitary gland causes an increased release of cortisol from the adrenal glands causing equine Cushing’s syndrome.
How does Prascend Equine work?
Pergolide is a synthetic ergot derivative and is a potent dopamine receptor agonist. As with other dopamine agonists, pergolide inhibits the release of prolactin. In horses with PPID, pergolide is believed to exert its therapeutic effect by stimulating dopamine receptors, and has been shown to decrease the plasma levels of adrenocorticotropic hormone (ACTH), melanocyte stimulating hormone (MSH), and other pro-opiomelanocortin peptides?
What is Horse Prascend used for?
Prascend tablets are used to control equine Cushing's disease (also referred to as hyperadrenocorticism). Cushings disease in horses can cause many symptoms. Clasically horses become more hairy and require more clipping than usual. Affected horses often develop a pot-bellied type appearance and can develop fat pads around the face and eyes in particular. Cushingoid horses are also more prone to lameness, laminitis is a particular problem. Other symptoms include an increased thirst and appetite, increased urination and increased infections. For example, wounds may take longer to heal than would be expected. Clinical improvement with Prascend is expected within 6 to 12 weeks. Some horses may respond clinically at lower or varying doses, and it is recommended to titrate to the lowest effective dose per individual based on response to therapy, whether it is effectiveness or signs of intolerance. A small number of horses may require doses as high as 10 µg/kg per day. In these rare situations, appropriate additional monitoring should be implemented. ?
How is Prascend given?
Prascend tablets may be administered orally by dissolving the tablet with a small amount of water and/or mixing with molasses or other sweetener; taking care to rinse the dosing apparatus with water to ensure entire dose of prascend is administered; use immediately. Most horses respond to prascend therapy and are stabilised at an average dose of 2 µg/kg.
How is horse Cushings diagnosed?
In some cases, vets may make a diagnosis of Cushings based simply on a clinical examination and an appreciation of the medical history of the horse or pony. In many cases however, your vet will want to take one or more blood samples from your horse in order to measure blood levels of various hormones or markers. The results of these tests can then be compared to "normal" ranges for the horse population, to confirm the presence of absence of the disease. Although a range of blood tests are available to assist the diagnosis and monitoring of cushings, the two most commonly used tests are: the Resting ACTH test – where a single blood sample is taken to measure the level of the hormone ACTH which is abnormally high in untreated cushings cases the Low dose Dexamethasone suppression test – where blood samples are taken before and after administration of a small dose of dexamethasone, to look for a "normal" response.
Prascend is available in 1mg tablet form
Prascend is a POM-V medication. A veterinary prescription must be provided prior to dispatch.
Pituitary pars intermedia dysfunction (PPID) is more commonly known as Cushing’s disease, and is a condition that can affect a wide range of mammals including horses. The condition in horses and ponies is caused when a tumour (known as a pituitary adenoma) develops in the pituitary gland, which interferes with the gland’s natural regulation of a stress hormone called cortisol. Cushing’s disease leads to the body producing an excess of cortisol, a naturally produced corticosteroid, which has a range of wide-reaching and varied effects on the body.
If your horse or pony has been diagnosed with PPID, it is important to learn about the basics of the condition, and also a good idea for all riders and horse and pony owners to be able to identify the symptoms of the condition. We will cover these factors in more detail within this article.
What are the symptoms of pituitary pars intermedia dysfunction in horses and ponies?
PPID or Cushing’s disease is more common in ponies than in horses, but all equines (including donkeys) may potentially develop the condition. The symptoms of the condition can be very slow in developing, but usually worsen over time. The core symptoms of the condition to be on the lookout for include:
How is PPID in horses and ponies diagnosed?
If you spot any of the above symptoms in your horse or pony, particularly if they progressively worsen over time, it is important to get your vet to come and check your horse over in order to get a firm diagnosis, and rule out other potential causes.
Your vet will talk to you about the symptoms that you have identified, examine your horse’s clinical history, and perform a full physical exam on your horse too. Generally, your vet will also need to take a blood sample from your horse and run a complete blood panel to diagnose the condition definitively, and work out the best way to proceed with treatment.
Can PPID be cured or treated?
Pituitary pars intermedia dysfunction or Cushing’s disease cannot be reversed or cured per se, but there are a variety of options available to you to manage the condition, improve your horse’s quality of life, and keep the disorder in check.
A medication called Prascend is one of the most commonly prescribed medications, which serves to regulate the pituitary gland’s cortisol production and keep it under control, and this medication needs to be given daily by mouth. Once treatment begins to take effect, your vet may review or reduce the dosage that your horse is given.
Other medications may be considered too, including Bromocriptine and Cyproheptadine, although these are not as popular or generally, as effective as Prascend.
Managing PPID after diagnosis
Once your horse or pony has been diagnosed with PPID, your vet will usually need to return to see your horse every few months to check the progression of the condition and how effective their medication is proving to be, and make any adjustments as needed. It is important that a horse or pony with PPID is kept at a suitable weight, as obesity and weight problems can exacerbate the condition. This may mean that horses that are usually kept partially or fully out on grass will be unable to graze freely after diagnosis.
PPID also serves to weaken the immune system of the horse on the whole, and so it is vitally important to check your horse over daily for scratches or other minor injuries, and these must be scrupulously cleaned and taken care of to minimise the possibility of an infection developing.
PPID also makes affected horses and ponies particularly prone to laminitis, which again, means that it is important to keep your horse’s weight under control and keep them away from lush, green pasture. You should inform your farrier of your horse’s diagnosis, as this information will help them to take proper care of your horse’s hooves, and spot the early signs of an impending problem.
Even if your horse or pony is not shod, it is important to arrange farrier visits regularly, in order to improve the chances of your farrier picking up on a problem early on.
When PPID has been brought under control and your horse or pony returns to their previous good condition, they should still be able to be ridden or otherwise work normally, providing that the rider makes allowances for the condition, and is alert to the signs of impending problems.
What is Previcox?
Previcox (or Firocoxib) is a POM-V category medicine that can be prescribed by your vet for the treatment of painful, inflammatory conditions such as arthritis or soft tissue injuries. Previcox is most widely available in tablet form that is usually very palatable. Previcox is available in 57mg or 227mg chewable tablet.
How Does Previcox work?
Previcox works by inhibiting the cell's production of chemicals that trigger inflammation
What is Previcox used for?
Previcox is useful in relieving the inflammation and pain associated with osteoarthritis. Osteoarthritis (Arthritis) is a painful condition that can affect an animal's joints. Arthritis is often seen in older animals due to the aging process, although some younger pets may develop this condition as a consequence of other illnesses such as hip dysplasia or cruciate disease in dogs.
How is Previcox Administered?
Previcox is given by mouth. It may be given with food to reduce the chance of stomach/intestinal side effects. Always follow the dosage instructions provided by your Vet. If you have difficulty giving the medication, contact your Vet for advice. Previcox should only be given to the pet for which it was prescribed. For long-term use, use the lowest dose needed to provide relief.
Previcox is available in strengths of 57mg Previcox and 227mg Previcox
A Veterinary Pet Prescription is Required for Previcox
Why is Previcox better than other NSAIDs?
Previcox is a non-steroidal anti-inflammatory drug (NSAID) prescribed for pain relief and inflammation related to osteoarthritis in dogs. It is also sometimes prescribed short-term for the management of post-operative pain in dogs.
Previcox is manufactured and distributed by Merial Animal Health, and contains the active ingredient Firocoxib.
Previcox is a relatively new product to enter the market, and has been compared favourably to competing products used for dogs in clinical trials. Previcox is a non-steroidal anti-inflammatory medication, which means that it works to reduce both pain and inflammation without the use of steroids, and is mainly indicated in the treatment of dogs suffering with osteoarthritis and related conditions.
Why might my dog be prescribed Previcox?
If your dog has been diagnosed with osteoarthritis, the next step for them involves working out a treatment and management regime to keep them as mobile as possible, and to reduce the pain and inflammation associated with the condition.
Exactly how your vet decides to proceed with treatment for your dog’s osteoarthritis will depend on a range of factors, including the age of your dog, how mobile they are, and the effect that the condition is having on their quality of life. Your vet will also likely dictate a feeding and exercise regime for your dog to ensure that their weight is kept within healthy parameters and so, does not place any additional pressure on their joints, in order to allow your dog to stay mobile and reduce the effects that the condition has on their day to day life.
As osteoarthritic pain can be exacerbated by a lack of movement, and yet the pain itself can make your dog reluctant to move for fear of pain, reducing the pain and inflammation associated with the condition by means of prescribed medications can help to keep your dog comfortable and active, and reduce the effects of osteoarthritic flare-ups.
Hydrotherapy, massage therapy or other forms of supportive treatments may also be used for dogs with osteoarthritis in conjunction with medication.
Previcox may also be prescribed in some cases for the management of post-surgical pain as a short term solution to aid with recovery.
How does Previcox work?
Previcox is one of the group of NSAIDs. NSAIDs work by inhibiting the production of chemical triggers by the body’s cells that produce inflammation. Different types of NSAIDs have slightly different actions, and so there is no one size fits all medication that is best across the board for all dogs.
The active ingredient in Previcox is Firocoxib, which is a medication from the coxib group. These medications work by selectively inhibiting the action of cyclo-oxygenase-2, or COX-2. This in turn leads to a reduction in pain and inflammation, and also has antipyretic properties for the reduction of heat or fever.
Firocoxib works by blocking the cyclo-oxygenase enzyme that is involved in producing prostaglandins. Prostaglandins can trigger pain, fever and inflammation, which means that Previcox reduces these effects.
How is Previcox administered?
Previcox comes in tablet form, and is given orally. Ideally, Previcox should be given with food to increase acceptance of the medication and reduce the possibility of stomach upsets as a result of taking the medication.
In the treatment of osteoarthritis in dogs, the normal dosage rate is 5mg/kg of bodyweight given once daily. The duration of treatment will be decided in conjunction with the prescribing veterinary surgeon.
For the treatment of post-operative pain, the normal dosage rate is 5mg/kg of bodyweight once per day for up to three days, beginning around two hours after surgery. Treatment may be extended after the initial three days if this is warranted.
What are the advantages of using Previcox over other NSAIDs?
The long-term usage of NSAIDs in dogs is not without its risks, and your veterinary surgeon should review your dog’s care and medication protocols regularly, weighing up the risks versus the benefits of their medications in order to make an informed decision on how to proceed with a view to preserving a good quality of life for the dog, and extending their healthy lifespan.
Previcox has been demonstrated to provide fast-acting pain relief to dogs with fewer adverse effects than alternative products, with clinical trials returning results of outstanding efficacy with a low rate of negative side-effects.
Previcox has proven superior to the administration of commonly prescribed alternative NSAIDs such as Carprofen or Etodolac in terms of the short term and potential long term side effects that such medications can produce, but as with all NSAIDs, treatment and dosage should be regularly reviewed and kept at the lowest viable dosage rate to provide relief.
How can I get Previcox for my dog?
Previcox is a POM-V medication, which means that your vet must approve treatment with Previcox and issue you with a prescription for it in order to allow you to buy it.
Once you have been provided with a prescription for Previcox, you can use your prescription to purchase the medication from us.
Pexion tablets are used to control primary ideopathic epilepsy in dogs. Pexion acts on specific receptors found within the brain to reduce the amount of excessive electrical activity that precipitates epileptic seizures. Pexion tablets have a number of advantages over other medications required to control epilepsy in dogs and is generally well-tolerated.
Pexion contains the active ingredient imepitoin and is available in the following strengths: 100mg Pexion and 400mg Pexion
A Veterinary Pet Prescription is required for Pexion
Treating dog epilepsy with Pexion
Pexion is a medication designed to treat primary epilepsy or idiopathic epilepsy in dogs, by reducing the amount of seizures that your dog suffers from, and limiting the overall effect that they have on your dog’s day to day life. The active ingredient in Pexion is Imepitoin, and Pexion comes in tablet form in doses of 100mg and 400mg respectively.
Why might my dog be prescribed Pexion Tablets?
Pexion may be prescribed to dogs diagnosed with primary or idiopathic epilepsy, which is, epilepsy for which the root cause is unknown. Prescription of Pexion for your dog should be considered carefully by your vet, after evaluation of the various alternative options.
Pexion is used to reduce the frequency rate of generalised epileptic seizures or fits in dogs, being the large-scale grand mal seizures that affect the whole of the brain.
How does Pexion work?
Pexion contains the active ingredient Imepitoin, which is an anti-epileptic drug. As epileptic seizures are triggered by storms of excessive electrical nerve impulses in the brain, Imepitoin works by partially activating the receptors for a neurotransmitter called gamma-aminobutyric acid or GABA, which allow the brain’s nerve cells to send messages to each other. GABA is responsible for partially reducing the electrical activity generated by firing nerve signals in the brain, and so by activating the brain’s GABA receptors, Imepitoin increases the effects of the GABA receptors, which helps to prevent seizures.
Imepitoin also has a limited effect on the calcium channels of the brain, pores that move calcium into the nerve cells to allow the transmission of electrical impulses, which in turn, helps to control seizures.
Is Pexion suitable for all dogs?
Pexion should not be used for dogs that have proven to be hypersensitive to Imepitoin or any of the inactive ingredients of the medication. Pexion is unsuitable for use in dogs with serious cardiovascular disorders, or severely impaired renal or hepatic function.
Pexion has not been trialled in dogs weighing less than 5kg, nor in dogs with chronic conditions such as renal, liver, heart or gastrointestinal disorders.
Pexion should not be used as the primary form of treatment for dogs that suffer from cluster seizures or status epilepticus (seizures that continue for more than 30 minutes at a time), as the medication has not been trialled for use in cases with this presentation.
How is Pexion administered?
Pexion comes in tablet form, and is given orally. The dosage rate for Pexion ranges from 10mg-30mg of Imepitoin per kg of the dog’s bodyweight given twice daily at twelve hourly intervals. Tablets are sold in 100mg Pexion or 400mg Pexion sizes and can be halved if appropriate.
Initial treatment usually involves using the lowest possible dosage rate for the size of the dog, with observation undertaken for the first week of treatment to ascertain its effectiveness. If the initial dose is well tolerated but does not prove as effective as it could be, the dosage rate can be increased up to a maximum of 30mg/kg per dose.
Pexion proves most effective when administered on an empty stomach, and as such, the timing of the dosage for the medication should be timed around meals to retain consistency and enable the drug to be given on an empty stomach.
Are there any side effects?
Pexion is generally well tolerated by dogs with few to no side effects, and any side effects that do present are usually transient, and will go away once your dog has got used to the medication.
During the initial stages of treatment, your dog may display some of the following symptoms:
Most of these side effects will remain very mild, if they present at all, and will usually go away on their own after a few days of treatment. Speak to your vet in the interim if you have any concerns about side effects, or if the side effects your dog experiences are very pronounced.
Do not stop giving your dog Pexion or alter their dosage without speaking to your vet first.
How can I get Pexion for my dog?
Pexion is a Pom-V medication, which means that it is a prescription-only product that is designed for use in dogs and can only be attained with a veterinary prescription.
Once your vet has decided that Pexion is the best form of treatment for your dog’s epilepsy, you ask your vet to issue you with a veterinary prescription that you can then use to purchase Pexion from us.
Palladia Tablets for Dogs are used for the treatment of non-resectable Patnaik grade II (intermediate grade) or III (high grade), recurrent, cutaneous mast cell tumours in dogs.
A Vet Prescription is required for Palladia
Treating mast cell tumours with Palladia
Palladia is a medication used for the treatment of mast cell tumours in dogs, and is one of the new wave of anti-cancer medications that have recently become approved for use in pets. In this article, we will look at mast cell tumours in more detail, as well as how Palladia works and why it is often indicated in mast cell tumour treatment. Read on to learn more.
What are mast cell tumours?
Mast cell tumours are also known as mastocytomas, and are a type of round cell tumour that develops from the body’s mast cells. Mast cells form a part of the body’s immune system, and are mainly utilised to generate a reaction to allergens, as well as being an integral part of normal wound healing and defending the body against pathogens.
Mast cells are produced in the bone marrow, and can be found throughout the body of the dog in connective tissue, as a normal part of the immune system. Mast cells produce histamine, which is one of the body’s responses to allergic reactions and tissue damage.
Mast cell tumours occur due to abnormal or excessive growth of the body’s mast cells, and mast cell tumours may be either malignant or benign. Mast cell tumours can appear in many parts of the body and take on many different appearances, but in the vast majority of cases, a mast cell tumour will be a standalone problem, with only 6% of cases presenting as multiple tumours.
When the body’s mast cells become a malignant tumour, they degranulate and create inappropriate inflammation of the surrounding tissues. Malignant mast cell tumours are highly inflammatory, and can spread throughout the body, sometimes worsening simply as the result of a biopsy or other manipulation.
Around 25% of all tumours diagnosed in dogs are mast cell tumours.
What is Palladia?
Palladia is an oral medication for the treatment of mast cell tumours in dogs. It is designed for the treatment of intermediate and high grade recurrent cutaneous mast cell tumours, or those affecting the skin, one of the most common sites for mast cell tumours.
Palladia was originally developed for use in humans, and was used off-label for the treatment of dogs for several years before it was awarded formal approval for canine use as the result of clinical trials.
How does Palladia work?
Palladia is made of the active ingredient Toceranib phosphate, which is a tyrosine kinase inhibitor. This means that Palladia acts against mast cell tumours in two different ways: Firstly it disrupts the blood supply to the tumour, and secondly, it kills the cells of the tumour itself.
This means that Palladia can reduce the size of the tumour, potentially eliminating it entirely, and also that it stops persistent or recurrent tumours from growing and developing.
Is Palladia suitable for use in all dogs?
Palladia should not be given to dogs under two years of age, or those that weigh less than 3kg. It is also not suitable for bitches that are pregnant or lactating, or that are intended to be used for breeding later on.
If the tumour is deemed as treatable with surgical intervention, this should be the first choice of treatment before Palladia is considered. Palladia is not suitable for dogs that suffer from gastrointestinal ulcers of bleeds.
Dogs that are prescribed Palladia should be monitored carefully to ensure that the drug is proving effective, and that any potential side effects of the medication are not negating the beneficial effects of the drug.
During the initial stages of treatment, the treatment protocol should be reviewed weekly for the first six weeks, and after this time, at six-weekly intervals or as advised by your veterinary surgeon.
Dosage and adjustments to the relevant dosage for any dog should be based on blood cell count and serum chemistry panels, as well as urinalysis and clinical observation.
How is Palladia given?
Palladia is provided in tablet form in different sizes, prescribed according to the bodyweight of the dog. The tablets can be given either with or without food, and should be swallowed. Generally, Palladia is given at the rate of one tablet per day, every other day. Always administer Palladia in accordance with your vet’s guidelines.
How can I get Palladia for my dog?
Palladia is a POM-V medication, meaning that it can only be bought with a veterinary prescription. If your vet recommends treating your dog’s mast cell tumour with Palladia, you can ask your vet to provide you with a veterinary prescription to buy the product from us.
Palladia should only ever be given to the dog for which it is prescribed, and you should not stop giving Palladia or change your dog’s dosage without first consulting with your vet first.