Therios for dogs and cats is used for the treatment of bacterial skin infections (including deep and superficial pyoderma) caused by organisms sensitive to cefalexin. Therios Tablets are also used for the the treatment of urinary tract infections (including nephritis and cystitis) caused by organisms sensitive to cefalexin.
Therios contains the active ingredient Cefalexin and is available in the following strengths: 300mg Therios and 750mg Therios and now 75mg Therios for Cats
A Veterinary Pet Prescription is required for Therios
Thyroxyl is used for the long term treatment of thyroid insufficiency in dogs. L-thyroxine is a synthetic product chemically identical to the naturally occurring thyroid hormone `T4'. Its effect is slow in onset, but of long duration.
Thyroxyl has now been discontinued by the manufacturer. Your Vet will prescribe an alternative medication for your dog, such as Soloxine
Trimediazine is indicated in the treatment of bacterial infections in horses caused by sensitive micro-organisms including: Escherichia coli Rhodococcus (Corynebacterium) equi Staphylococcus spp. Streptococcus spp. Trimediazine may also be effective in alimentary tract infections including diarrhoea; respiratory tract infections including pneumonia; pleurisy and strangles; wounds, septicaemia and general infections.
Trimediazine contains the active ingredients Trimethoprim and Sulfadiazine and is available in the following strengths: 50g Trimediazine Sachets
A Veterinary Pet Prescription is required for Trimediazine
Trusopt Eye Drops are used to treat glaucoma when treatment with a beta-blocker eye drop on its own has not lowered the pressure in the eye sufficiently.
Trusopt contains the active ingredient and is available in the following strengths:
A Veterinary Pet Prescription is required for Trusopt
Tylan soluble is used for the prevention and control of swine dysentery and enzootic pneumonia. Treatment and control of Lawsonia intracellularis, the organism associated with Porcine Proliferative Enteropathies such as Porcine Intestinal Adenomatosis (Ileitis) and Porcine Haemorrhagic Enteropathy.
A Veterinary Prescription is required before we can dispense Tylan. Please do not order this medication unless you have, or are in the process of obtaining a Veterinary Prescription.
Regumate is for use in mares with significant follicular activity during the transitional period between seasonal anoestrus and in the breeding season
Horse shows are a major investment – and you’ve got less than 10 minutes in the ring to make it all pay off. That’s why it’s so important for your mare to be at the top of her game every time she enters the ring. If your mare’s behavior and focus change when she’s in heat, she can not only cost you the class, she can cost you the hundreds of pounds it took to get her there.
You can help reduce undesirable changes in behavior and mood by suppressing your mare’s estrous (heat) cycle with Regumate (altrenogest). Within three days of the start of treatment, Regumate will effectively suppress estrus in 95 percent of mares (It’s important to note Regumate cannot improve your mare’s performance from what it is normally. Regumate can only eliminate hormonal distractions so she can focus on you and perform more predictably.)
Regumate the proven performer for performance mares When you’re campaigning a mare, every advantage counts. That’s why more and more trainers are turning to Regumate to suppress estrus and make their mares’ performances more predictable. Regumate effectively suppresses estrus in 95 percent of mares after 3 days of treatment. When treatment is discontinued, mares exhibiting regular estrous cycles return to estrus within 4 to 5 days following treatment and continue to cycle normally.
Regumate can help alleviate moodiness and temperament changes associated with estrus. It’s easy to administer – orally or top-dressed on grain. Talk to your Vet about proper use and safe handling of Regumate. Avoid skin contact. Always wear protective gloves when administering Regumate. This product is contraindicated for use in mares with a previous or current history of uterine inflammation. Pregnant women, or women who suspect they are pregnant, should not handle this product.
A Veterinary Prescription is required for Regumate
Use of Regumate in horses
Regumate Equine is a hormonal medication for mares, distributed in the UK by MSD Animal Health. It can be used to prevent or supress the oestrus cycle in mares, restore a regular oestrus cycle, and may also be used as a strategic tool to aid with selective or planned breeding.
Regumate contains the active ingredient altrenogest, which is a hormone that can be used to supress the oestrus cycle in mares of breeding age, while also allowing for a predictable return of the normal cycle after withdrawal of the medication. This means that the medication can be used to enable regular oestrus cycles in the mare, as well as achieving a reliable transition from the winter season’s anoestrus to the normal return to fertility of the spring and summer seasons.
Supressing the oestrus cycle with Regumate can also help with the management of various health conditions related to the oestrus cycle and reproductive system, and Regumate may also be used to facilitate planned mating during the physiological breeding season.
Why might my mare be prescribed Regumate?
There are various different indications for the use of Regumate in mares of breeding age, which your vet should discuss with you in detail. The main uses of Regumate in mares are as follows:
Is Regumate suitable for all mares?
Regumate is unsuitable for use in mares that have been diagnosed with a uterine infection. Clinical trials of Regumate have demonstrated that around 95% of all mares treated with Regumate will undergo oestrus suppression within three days of the commencement of treatment, however, how quickly any mare will return to normal oestrus cycles after treatment has stopped largely depends on the level of ovarian activity present when the treatment started.
Regumate should only be administered to the mare for which it has been prescribed.
How is Regumate administered?
Regumate is sold as a liquid for oral administration, and as a hormonal product, care should be taken when administering and handling the product. Wear gloves to avoid the absorption of the product via the skin. Pregnant women should avoid handling or administering Regumate.
Regumate can be added to the mare’s feed, or delivered directly by mouth using the supplied syringe. Regumate is supplied with a pre-marked dosing syringe, and the appropriate dosage should be drawn up into the syringe and carefully checked. A dosage cap for adding Regumate to food is also provided, and if adding to food, the appropriate dose should then be poured into the measuring compartment.
Are there any side effects?
Regumate is generally extremely well tolerated by mares, and is highly unlikely to produce any undesirable side effects. While the product is not designed for use in mares that are already in foal or that are producing milk, no negative effects have been observed in either the mare or the foal in conjunction with the use of Regumate.
Adverse reactions to Regumate are extremely rare, and there are no specific observed side effects or reactions recorded in relation to the medication.
The use of Griseofulvin for your mare may alter the effects of Regumate if the two products are administered concomitantly.
How can I get Regumate for my horse?
Regumate is a POM-V medication, which means that you will require a veterinary prescription in order to buy it. Once your vet has approved the use of Regumate for your horse, they can provide you with the necessary prescription to enable you to buy Regumate from us.
Stronghold is used for the treatment and prevention of flea infestations and roundworms for one month following a single administration
Stronghold contains the active ingredient selamectin and is available in the following strengths: 15mg Stronghold, 30mg Stronghold, 45mg Stronghold, 60mg Stronghold, 120mg Stronghold and 240mg Stronghold
A Veterinary Pet Prescription is required for Stronghold
Ronaxan is used for the treatment of respiratory tract infections in cats and dogs, including rhinitis, tonsillitis, bronchopneumonia and feline respiratory disease. The therapeutic spectrum includes Pasteurella spp., Bordetella bronchiseptica, Staphylococcus aureus, other Staphylococcus spp. and Streptococcus spp
Ronaxan contains the active ingredient doxycycline and is available in the following strengths: 20mg Ronaxan and 100mg Ronaxan
A Veterinary Pet Prescription is required for Ronaxan
Rilexine is used for the treatment of the infections caused by bacteria sensitive to cephalexin, such as infections of the urinary tract in cats and dogs (such as nephritis and cystitis). Rilexine is used for the treatment of cutaneous infections (pyoderma) in dogs, including skin fold pyoderma impetigo, folliculitis, furunculosis and cellulitis.
Rilexine contains the active ingredient cephalexin and is available in the following strengths: 75mg Rilexine, 300mg Rilexine and 600mg Rilexine
A Veterinary Pet Prescription is required for Rilexine
What is Synulox?
Synulox is an antibiotic containing the active ingredients amoxicillin and potassium clavulanate and is licensed as a treatment for infections in dogs, cats, cattle and pigs. Occasionally Synulox will be used to treat infections in other animals such as sheep and goats. Synulox is available as palatable pink tablets, an oral suspension, a yellow, injectable suspension and intra-mammary tubes and is a prescription-only medicine (POM-V). This means that VetDispense and other online pet pharmacies always require a prescription, written by your vet before dispensing any formulation of synulox.
How does Synulox work?
Synulox contains 2 main active ingredients: Amoxicillin and Clavulanic acid. Amoxicillin is known as a ?-Lactam Antibiotic. The main feature of this group of antibiotics is to prevent the formation of a bacterial cell wall (specifically, the production of the peptidoglycan layer is inhibited). Since the bacterial cell wall is essential for bacterial function (especially gram-positive bacteria), amoxicillin is classed as bacteriocidal (able to destroy the bacteria). One big problem that Vets encounter with amoxicillin is bacterial resistance. This is because bacteria are increasingly becoming able to synthesise an enzyme that is responsible for breaking down the ?-Lactam ring. This renders the antibiotic ineffective and it is for this reason that clavulanic acid is combined with amoxicillin to form synulox. Clavulanate can block the enzyme (?-Lactamase), allowing the amoxicillin to interfere with bacterial cell wall production and cause bacterial distruction.
What is Synulox used for?
Synulox is a broad-spectrum antibiotic. This means that Synulox is able to destroy a wide range of gram-positive and some gram-negative bacteria. Synulox is used by Vets to treat some of the more common infections affecting the mouth, skin, urianary tract, respiratory tract and gastrointestinal system. Bacterial infections can cause a number of symptoms, for example skin infections tend to cause redness and pain, can be painful to the touch, can sometimes discharge fluid and can occasionally smell unpleasant. Urinary tract infections such as bladder infections or cystitis can be painful and cause animals to show signs of abnormal urination (e.g. urinating more frequently than normal, straining, passing red coloured fluid). If you suspect that your pet may have an infection, you should always arrange an appointment with your vet urgently. There are many diseases that can have similar symptoms so it is essential that your vet establishes a diagnosis and rules out the possibility of a more serious underlying condition. Occasionally, your vet may want to find out exactly what sorts of bacteria are affecting your pet (particularly if an infection is not responding as expected) and will consider taking some samples (e.g. a swab or fluid sample). These samples are then analysed in the laboratory and microbiologists perform culture and sensitivity tests. These tests let vets know which antibiotic is most appropriate, establishes whether any resistance exists, and enables more effective treatment of patients. Antibiotic resistance is increasingly becoming a problem amongst both animals and humans. It is for this reason that antibiotics are only available on prescription from your vet. It is important that all the instructions are followed precisely and that the course of antibiotics is completed without any doses being missed. Buying antibiotics such as synulox without a vet prescription is illegal in the UK. Any websites or companies selling antibiotics without prescription are likely to be providing counterfeit medicines that could put your pet’s health at risk.
How is Synulox administered?
Synulox can be administered by injection under the skin or into the muscle. The route of injection varies depending on the species of animal being treated. Synulox can also be administered orally using palatable tablets or a palatable suspension. The Synulox palatable suspension is more commonly used to treat smaller animals such as puppies or kittens. Synulox lactating cow is used as a treatment for mastitis in cattle and is available as an intramammary suspension. This is useful for the treatment of Staphylococci, Stretococci and Escherichia coli.
Synulox is available as: Synulox 50mg palatable tablets, Synulox 250mg palatable tablets, Synulox 500mg palatable tablets, Synulox palatable drops, Synulox lactating cow intramammary tubes & Synulox suspension for injection
A Veterinary Prescription is Required for Synulox
Trocoxil is a prescription-only medication used for the treatment of pain and inflammation associated with degenerative joint disease or osteoarthritis in dogs aged 12 months or more.
Trocoxil contains the active ingredient Mavacoxib and is a relatively new treatment for arthritis in dogs. Trocoxil is available in brown tablet form (with Pfizer embossed onto the tablet) and in strengths of 6mg, 20mg, 30mg, 75mg or 95mg. In comparison with other arthritis treatments in animals, Trocoxil can be administered relatively infrequently due to the drug's prolonged duration of action.
Trocoxil is a non-steroidal anti-inflammatory drug (NSAID). Trocoxil works by inhibiting an enzyme known as cyclooxygenase (particularly cyclooxygenase-2) that is responsible for prostaglandin synthesis. By stopping this enzyme (COX-2) from working, the inflammatory effect is reduced and animals become more comfortable. Because osteoarthritis is an inflammatory condition, Trocoxil and other NSAIDs are highly effective at controlling this form of pain and often bring much needed relief to a stiff, sore and arthritic animal. Many owners report that their pet has a 'new lease of life' following the use of Trocoxil.
Trocoxil is a POM-V medication
A Veterinary Prescription is Required before we can dispense Trocoxil to a UK address
Trocoxil: The monthly NSAID
Trocoxil is the trade name for the Non-steroidal anti-inflammatory drug (NSAID) Mavacoxib, which is designed for the treatment and management of degenerative joint disease in dogs. Trocoxil is distributed in the UK by Zoetis UK Limited, and is a relatively new addition to the veterinary NSAID arsenal.
Trocoxil is an NSAID from the same class as some other widely used medications such as Metacam and Rimadyl, but with one significant difference. Trocoxil has a very slow release rate, and is eliminated from the body of your dog much less quickly than the alternatives, which means that after your dog is treated with an initial loading dose, they will only need to be administered with the medication once a month.
This eliminates the need for daily medications, and so removes the many challenges that can accompany this, such as a lack of compliance from the dog, the difficulties of keeping to a regular schedule, and the problems of forgetting the occasional dose.
Why might my dog be prescribed Trocoxil?
Trocoxil is indicated in the treatment of degenerative joint disease in dogs, such as arthritic pain and other chronic conditions that lead to inflammation, swelling, heat and pain in the joints.
Conditions such as these cannot be surgically corrected or fully cured, and so keeping your dog comfortable and happy with a good quality of life depends on the day to day management of their condition, which in turn, usually relies upon a combination of factors.
Keeping your dog’s weight within healthy parameters can help to reduce pressure on the joints and the pain that can accompany this, and physical therapies can also help to extend your dog’s range of movement and the suppleness of their joints. However, in order to address the pain, swelling and inflammation that accompany degenerative joint conditions in the dog, NSAIDs are commonly used to keep your dog comfortable and allow them to retain a good range of mobility in comfort.
Trocoxil is one of several NSAIDs that your vet may consider prescribing for your dog, and if your dog is already undergoing treatment with a daily pill or other medication, it may be worth asking your vet to consider changing your dog over to Trocoxil. As Trocoxil is administered monthly and not daily, the product provides numerous advantages for dog owners when compared to alternatives.
How does Trocoxil work?
Trocoxil contains the active ingredient Mavacoxib, which is part of the class of medications called NSAIDs, and has both anti-inflammatory and analgesic properties.
Mavacoxib inhibits the cyclo-oxygenase (COX) enzymes, and has a preferential effect on COX-2 over Cox-1, which means that the occurrence rate of side effects such as gastrointestinal symptoms is lower when compared to nonselective products.
Mavacoxib is eliminated from the body much more slowly than alternative products, resulting in a prolonged anti-inflammatory effect on inflamed joints, and means that the medication needs only to be given once a month after an initial two week loading dose.
How is Trocoxil administered?
Trocoxil comes in tablet form, and is taken orally. After the initial two week loading dosage, the dosage rate for Trocoxil is 2mg/kg of bodyweight given once per month. Trocoxil should be administered with food, to increase its uptake rate by the body.
Is Trocoxil suitable for all dogs?
As with all NSAIDs, the use of Trocoxil should be carefully considered, as over time, NSAIDs may compromise some of the body’s core functions. Certain dogs should not be prescribed Trocoxil, or may be more sensitive to suffering from ill effects of the medication. The following guidance is provided for the use of Trocoxil in dogs:
How can I get Trocoxil for my dog?
Trocoxil is one of several NSAIDs that your vet may consider prescribing to your dog, and they should discuss the options with you in detail, as well as their merits and potential downsides.
If your vet decides that Trocoxil is the best option for your dog, they can issue you with a veterinary prescription to allow you to purchase Trocoxil from us.
Rimifin is used for the reduction of inflammation and pain caused by musculo-skeletal disorders and degenerative joint disease. Rimifin is also used as a follow up to parenteral analgesia in the management of post-operative pain following soft tissue surgery.
Rimifin contains the active ingredient carprofen and is available in the following strengths: 20mg Rimifin, 50mg Rimifin and 100mg Rimifin
A Veterinary Pet Prescription is required for Rimifin
Surolan is used for the topical treatment of otitis externa and skin infections caused by Gram-positive bacteria e.g. Staphylococcus aureus and Streptococcus spp. and Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa. Surolan is used for the topical treatment of otitis externa and skin infections caused by fungi and yeasts: Trichophyton spp., Microsporum spp., Malassezia pachydermatis, Candida spp. Surolan Drops are used for the topical treatment of otitis externa caused by the ear mite Otodectes cynotis. Surolan also has anti-inflammatory and anti-pruritic activity.
Surolan is for topical administration. Shake the bottle of Surolan well and ensure the product is fully resuspended before use. At the beginning of treatment, hair surrounding or covering the lesions must be clipped; this should be repeated during treatment with Surolan if necessary.
Surolan Drops are available in the following sized bottles:15ml Suroland and 30ml Surolan
A Veterinary Prescription is Required for Surolan
Soloxine is given once or twice daily to dogs with low levels of thyroid hormone (hypothyroidism). For the long term treatment of thyroid insufficiency - hypothyroidism - in dogs. L-Thyroxine is a synthetic product chemically identical to the naturally occurring thyroid hormone `T4'. Its effect is slow in onset, but of long duration. Some of the clinical signs of hypothyroidism in dogs include: Skin and coat changes including hair loss and myxedema Recurrent ear infections (otitis) Heat seeking behaviour 'Tragic' facial expressions Obesity Lethargy Anaemia High cholesterol levels Reproductive problems
Soloxine contains the active ingredient L-Thyroxine Sodium and is available in the following strengths: 0.1mg Soloxine, 0.2mg Soloxine, 0.3mg Soloxine, 0.5mg Soloxine and 0.8mg Soloxine
A Veterinary Pet Prescription is required for Soloxine
Seresto Collars are used for the treatment and prevention of flea (Ctenocephalides felis) infestation in cats and dogs. Protection against fleas starts immediately after application of the collar and lasts up to 8 months! Protects the animal’s immediate surroundings against flea larvae development for 10 weeks
Seresto Collars contains the active ingredients imidacloprid and flumethrin and is available in the following sizes: Seresto for Cats, Seresto for Dogs under 8kg and Seresto for Dogs over 8kg
A Veterinary Pet Prescription is required for Seresto Collars
A Veterinary Prescription is Required for Sedalin
Thyforon for Dogs are used for the treatment of hypothyroidism in dogs. The tablets are round, off white in colour with brown spots. They are scored into quarters and can be divided into halves or quarter according to the dose required by your Dog.
Thyforon Tablets are available in the following strengths: Thyforon 200, Thyforon 400 and Thyforon 800
A Veterinary Pet Prescription is required for Thyforon
Hypothyroidism in dogs Hypothyroidism is a relatively common condition in the dog, and is caused when the thyroid gland does not naturally produce enough of a hormone called thyroxine, which controls the metabolism of the dog to convert the dog’s food into fuel for life. The condition can occur for a wide variety of reasons including tumours, a shrinking thyroid gland and due to immune system imbalances, but the good news is that the condition can generally be managed and treated very successfully on an outpatient basis.
Are certain types of dog more prone to the condition than others?
As a fairly common canine condition, hypothyroidism can potentially affect any breed or mixed breed of dog, but it is particularly common in the Dachshund, Golden Retriever, Doberman, Boxer and Cocker Spaniel. The condition does not generally become apparent until the dog is at least four years old, and is more likely to occur in large breeds, and in neutered dogs of either sex.
What causes hypothyroidism to develop?
The root cause of the condition is not always obvious, but some of the known causes of the condition include:
• Cancers and tumours that affect the thyroid gland.
• Congenital conditions.
• As a side effect of certain medications and surgical treatments.
• Iodine deficiencies.
What are the symptoms of hypothyroidism in dogs?
A relatively wide range of different symptoms can be seen as part of the condition, which can make it hard to definitively identify. Dog owners are advised to stay vigilant to the following symptoms, which may not all be apparent but that often appear in combination:
• Reluctance to exercise and general lethargy.
• Muscle weakness.
• Weight gain for no apparent reason.
• Loss of fur and excessive shedding.
• A dry, dull or otherwise poor condition coat.
• Persistent or recurrent skin infections with no obvious cause.
• A tendency to feel the cold more than normal.
• In rare cases, head tilting or even seizures may occur.
How is hypothyroidism diagnosed?
Your vet will need to make a physical examination of your dog, as well as looking at their clinical history and talking to you about the signs and symptoms that you have noticed at home. If your vet suspects hypothyroidism, they will then perform some blood and urine panels on your dog, which may be enough to diagnose or rule out the condition.
However, in many cases, your vet will also need to perform endocrine tests to determine the levels of the T3 and T4 hormones (thyroid hormones) present within the body, and determine whether or not these are within normal parameters or lower than they should be. A radiograph may also be performed, to see if there is a problem or abnormality underlying the condition that can be treated.
Can hypothyroidism in the dog be treated?
Hypothyroidism in the dog cannot be reversed or cured, but it can be effectively managed. This will require the administration of supplemental thyroid hormones such as Thyforon or Soloxine to correct the body’s underproduction of their natural hormones, and your dog will require daily medications such as these for the remainder of their life to keep the condition under control.
Fortunately, the daily cost of administering medications such as these amounts to just a few pence, and so after diagnosis, the condition is not costly to manage.
Once your dog’s thyroid hormone levels have been brought under control, the symptoms of the condition will usually resolve themselves within a few weeks or months, returning your dog to their old selves.
Care and management of hypothyroidism
In order to keep the condition under control and keep your dog in good health, it is important to administer your dog’s medications regularly and in accordance with your vet’s guidelines. You will also likely need to make return visits to the clinic every few months so that your vet can monitor your dog’s thyroid levels, and make any necessary adjustments to their medications.
When your dog has first been diagnosed with hypothyroidism, your vet will also likely recommend feeding a special diet such as Hill’s R/D, to reduce their fat intake. Often, a special diet of this type is only necessary during the initial phase of treatment, until the condition is brought under control.
Dogs with hypothyroidism will generally lead an otherwise normal life once their condition is under control, and will be able to perform all of the activities that other dogs can, and usually live to old age in good health.
While a diagnosis of hypothyroidism can be worrying for the owner, it is one of the easiest and best known condition to treat on an ongoing basis, and should not affect the dog’s quality of life or wellbeing on the whole.
Semintra has a highly targeted mode of action that provides rapid and reliable reduction in proteinuria in cats with chronic kidney disease
VET PRESCRIPTION REQUIRED