225mg Credelio Tablets for Dogs - Pack of 6

225mg Credelio Tablets for Dogs - Pack of 6 View larger
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Credelio Chewable Tablets for dogs are beef flavoured tablets used for the treatment of flea and tick infestations. VETERINARY PRESCRIPTION REQUIRED.

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915300

Data sheet

Target Animal:Dog (Canine)
Related Condition:For the treatment of flea and tick infestations in dogs.
Pet Prescription Required?:Yes
Active Ingredient:Lotilaner
Product Name:Credelio Tablets for Dogs
Pack Size:Pack of 6

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225mg Credelio Tablets for Dogs - Pack of 6

Credelio may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Credelio if you have or are in the process of arranging such a prescription. See information bar for further details.

For dogs weighing 5.5kg - 11kg

Credelio Tablets are used for the treatment of flea and tick infestations in dogs. Credelio provides immediate and persistent killing activity for 1 month for fleas (Ctenocephalides felis and C. canis) and ticks (Rhipicephalus sanguineus, Ixodes ricinus, I. hexagonus and Dermacentor reticulatus). Fleas and ticks must attach to the host and commence feeding in order to be exposed to the active substance.

Credelio can also be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD). Do not use Credelio in case of hypersensitivity to the active substance or to any of the excipients. Special warnings for each target species Parasites need to start feeding on the host to become exposed to Credelio; therefore the risk of the transmission of parasite borne diseases cannot be completely excluded. Special precautions for use Special precautions for use in animals All safety and efficacy data have been acquired from dogs and puppies 8 weeks of age and older and 1.3 kg of body weight and greater. Use of Credelio in puppies younger than 8 weeks of age or less than 1.3kg of body weight should be based on a benefit-risk assessment by the responsible veterinarian. Special precautions to be taken by the person administering the veterinary medicinal product to animals Wash hands after handling Credelio. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or label to the physician.

Credelio, a pure enantiomer from the isoxazoline class is active against fleas (Ctenocephalides felis and Ctenocephalides canis) as well as the tick species Dermacentor reticulatus, Ixodes hexagonus, Ixodes ricinus and Rhipicephalus sanguineus. Lotilaner is a potent inhibitor of gamma–aminobutyric acid (GABA)-gated chloride channels, resulting in rapid death of ticks and fleas. The activity of lotilaner was not affected by resistance to organochlorines (cyclodienes, e.g. dieldrin), phenylpyrazoles (e.g. fipronil), neonicotinoids (e.g. imidacloprid), formamidines (e.g. amitraz) and pyrethroids (e.g. cypermethrin). For fleas, the onset of efficacy is within 4 hours of attachment for one month after product administration. Fleas on the animal prior to administration are killed within 6 hours.

For ticks, the onset of efficacy is within 48 hours of attachment for one month after product administration. Existing I. ricinus ticks on the animal prior to administration are killed within 8 hours. Credelio kills existing and newly emerged fleas on dogs before they can lay eggs. Therefore, Credelio breaks the flea life cycle and prevents environmental flea contamination in areas to which the dog has access. Pharmacokinetic particulars Following oral administration, lotilaner is readily absorbed and peak blood concentration is reached within 2 hours. Food enhances the absorption. The terminal half-life is approximately 4 weeks. This long terminal half-life provides effective blood concentrations for the entire duration of the inter- dosing interval. The major route of elimination is biliary excretion and renal excretion is the minor route of elimination (less than 10% of the dose). Lotilaner is metabolized to a small extent into more hydrophilic compounds which are observed in faeces and urine. Pharmaceutical particulars List of excipients Cellulose, powdered Lactose monohydrate Silicified microcrystalline cellulose Meat dry flavour Crospovidone Povidone K30 Sodium laurilsulfate Silica, colloidal anhydrous Magnesium stearate Incompatibilities Not applicable. Credelio does not require any special storage conditions.

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Credelio is a POM-V (Pet Prescription is required)