20mg Librela Solution for Dogs - 2 Vials
370952
Librela 20mg is a new injecton used for arthritis pain relief in dogs. Librela is scientifically proven to ease pain effectively for an entire month. With minimal liver, kidney, and GI involvement, Librela's monoclonal antibodies offer a safer, more natural approach to treating osteoarthritis in dogs.
Librela provides an innovative alternative to NSAIDs by targeting the Nerve Growth Factor (NGF), known for inducing pain and inflammation in osteoarthritis. Dogs show a marked increase in mobility and reduction in pain after the first dose, making it an ideal choice for pain management. Librela is administered as a subcutaneous injection, usually once a month, by a veterinary surgeon or at home if your Vet has given you some training.
Librela is a refrigerated medication - We will send it via Royal Mail Special Delivery using insulated packaging and ice packs. A signature is required on delivery and it must be put straight into a fridge. We cannot guarantee same day dispatch for orders placed after 12pm. VETERINARY PRESCRIPTION REQUIRED.
Librela 20mg is a caninised monoclonal antibody. Each vial of 1ml Librela contains 20mg bedinvetmab and enhances the natural process of clearing away immune complexes, thus avoiding pain signals from reaching the brain and causing neuropathic pain.
Osteoarthritis, often referred to as arthritis, is a long-term joint condition that causes pain, stiffness and reduced mobility. Dogs may find it harder to rise after rest, climb stairs, jump into the car, or keep up on walks. Managing pain can help maintain activity and muscle, which supports joint function.
Osteoarthritis commonly affects weight-bearing joints such as hips, elbows and knees, but it can also involve the spine. When a dog moves less due to pain, muscle support reduces and joints can become stiffer, which may worsen the cycle of discomfort. For this reason, long-term management often focuses on keeping movement comfortable and consistent, rather than waiting until a dog is severely lame.
How 20mg Librela works
Librela contains bedinvetmab, a canine monoclonal antibody. A monoclonal antibody is a targeted protein therapy designed to bind to a specific substance in the body. Bedinvetmab targets nerve growth factor (NGF), which is involved in pain signalling and in the "turning up" of pain sensitivity.
In osteoarthritis, NGF activity around affected joints can contribute to ongoing discomfort. When bedinvetmab binds to NGF, it helps reduce NGF‑mediated signalling. This can lower pain signalling from the joint and improve comfort. Librela does not repair cartilage or reverse structural joint changes. It is intended to manage pain so that supportive measures, such as controlled exercise and weight management, are easier to maintain.
Product Features
- Pack Size: - Pack of 2
- Target Animal: - Dog (Canine)
- Related Condition: - Osteoarthritis in Dogs
- Pet Prescription Required?: - Yes
- Active Ingredient: - Bedinvetmab
- Product Name: - Librela solution for injection for dogs
More Information
Description
How Librela works
Librela contains bedinvetmab, which is a canine monoclonal antibody. Monoclonal antibodies are proteins designed to bind to a specific target in the body. Bedinvetmab targets nerve growth factor (NGF), a naturally occurring protein involved in pain signalling. In osteoarthritis, NGF contributes to the transmission and amplification of pain signals from affected joints.
After injection, bedinvetmab binds to NGF and reduces NGF-mediated cell signalling. This can reduce the sensation of osteoarthritis pain. Librela works differently from many traditional pain-relief medicines, such as non-steroidal anti-inflammatory drugs (NSAIDs). Your veterinary surgeon will decide whether Librela is suitable for your dog and how it fits alongside any other treatments.
Response times vary. Some dogs show improvement within the first week, while others need longer. If the response after the first dose is limited, some dogs show additional improvement after a second dose given one month later. If there is still no meaningful benefit after two doses, your veterinary surgeon may recommend an alternative approach.
Librela is supplied in different strengths to match a labelled dosing schedule based on bodyweight. The 20mg vial contains 1 ml of solution and is commonly used for dogs in the 30.1 kg to 40.0 kg bodyweight range, as part of the dosing table. Your veterinary practice will select the most appropriate strength based on an accurate weight.
Librela is not suitable for every dog. It should not be used in dogs under 12 months of age. It should not be used in pregnant or lactating animals, or in animals intended for breeding. It should not be used in dogs with known hypersensitivity to the active substance or excipients. If your dog has other medical conditions, or is taking other medicines, your vet will take this into account when prescribing.
Arthritis (osteoarthritis) in dogs
Canine osteoarthritis is a long-term joint condition that causes pain, stiffness and reduced range of motion. It involves cartilage wear, inflammation within the joint, and changes to surrounding tissues and bone. Osteoarthritis can affect any joint, but hips, elbows, knees, shoulders and the spine are common sites.
Typical causes and risk factors include age, previous injury (such as cruciate ligament disease), hip or elbow dysplasia, and excess bodyweight. Symptoms often fluctuate. Many dogs have a baseline level of stiffness with occasional flare-ups after heavier activity.
Early signs can be subtle. You might notice stiffness when rising, limping, slowing down on walks, reluctance to jump or climb stairs, difficulty getting into the car, or reduced interest in play. Behaviour can also change, including irritability or reduced tolerance of handling around painful joints.
If you suspect arthritis, a veterinary assessment is important. Other problems can look similar, including paw pain, soft tissue injury and neurological conditions. Your vet may diagnose osteoarthritis based on history and examination and may recommend imaging such as X-rays to support the diagnosis and guide treatment.
Managing arthritis
Most dogs benefit from a combined plan that addresses pain and daily movement.
Weight control reduces load on joints and can make a noticeable difference to comfort. Your veterinary practice can advise on an appropriate diet and safe, realistic weight loss where needed.
Regular, controlled exercise is usually better than intense, sporadic activity. Short, steady walks can maintain fitness without repeated flare-ups. If your dog has been inactive due to pain, increases in activity should be gradual.
Physiotherapy and rehabilitation can improve strength and balance. Simple home changes can also help, including non-slip mats, supportive bedding and ramps for steps or cars. Some dogs also benefit from joint-support diets or supplements, chosen with veterinary advice.
Librela can be used as part of a long-term osteoarthritis management plan. Monthly administration can suit dogs that struggle with daily tablets, and it provides a consistent approach that can be reviewed regularly by your vet. Librela may be used on its own or alongside other treatments, depending on your dog’s needs and overall health.
Some dogs with arthritis also receive NSAIDs or other pain-relief medicines. Your veterinary surgeon will decide what combination is appropriate and whether monitoring is needed. Librela should not be mixed with other veterinary medicinal products in the same syringe.
Handling and storage
Librela should be stored and transported refrigerated at 2°C to 8°C. It should not be frozen. It should be kept in the original packaging and protected from light. Once opened, it should be used immediately. If your order is delivered, it should be placed into a refrigerator promptly on arrival.
How quickly does Librela start working?
Some dogs show improvement within the first week, while others need longer. If the response after the first dose is limited, additional improvement may be seen after the second monthly dose. Your vet should review progress and decide whether continuing treatment is appropriate for your dog.
Is Librela a steroid or an NSAID?
Librela is not a steroid and it is not a non-steroidal anti-inflammatory drug (NSAID). It is a monoclonal antibody that binds to nerve growth factor (NGF), which is involved in transmitting pain signals. This different mechanism can be useful in selected dogs under veterinary guidance.
Can Librela be used with other arthritis medicines?
Your vet may use Librela alongside other treatments, depending on your dog’s overall health and response. Some dogs also receive NSAIDs, physiotherapy or other pain-control options. Treatment combinations should be planned by a veterinary surgeon, rather than adding medicines without advice, and reviewed regularly
What side effects can occur with Librela?
Side effects can include mild injection site swelling or warmth. Less commonly, increased thirst and urination, urinary incontinence, unsteadiness, lethargy, diarrhoea, vomiting or reduced appetite can occur. Very rarely, hypersensitivity reactions have been reported. Contact your vet promptly if you are concerned.
How should Librela be stored at home?
Librela should be kept refrigerated at 2°C to 8°C in the original packaging and protected from light. It should not be frozen. If it is delivered to your home, place it in the refrigerator promptly to maintain the cold chain. Follow the label instructions and your veterinary practice’s advice.
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