menu Menu Search
What are you looking for? close
RCVS Registered: 7025700
Run by a qualified team of Vets
First Class Delivery only £3.99
Next Day Delivery available
  • New
15mg Zenrelia for Dogs - Per Tablet
View Larger

15mg Zenrelia for Dogs - Per Tablet

961218

£1.49 (inc. VAT)

15mg Zenrelia for Dogs

15mg Zenrelia for Dogs is a prescription medicine used to help manage the itch and skin inflammation associated with allergic skin disease, including atopic dermatitis (atopy). Zenrelia is intended for dogs that have been examined by a veterinary surgeon and diagnosed with an allergic condition. Zenrelia 15mg is used as part of a wider care plan that may include parasite control, skin and ear care, environmental changes, and nutrition.

How Zenrelia for Dogs works

Zenrelia acts on the pathways that drive itch and inflammation during an allergic flare. In dogs with atopy, the immune system reacts strongly to otherwise harmless substances such as pollen, house dust mites, moulds, or other environmental allergens. This reaction releases chemical messengers that signal itch, redness, heat, and swelling in the skin. Zenrelia Tablets help to reduce these signals. By moderating the activity of key immune messengers and the cells that release them, the medicine lowers the intensity of the itch response and helps calm inflamed skin. As the impulse to scratch and lick reduces, the skin surface has a better chance to recover, which in turn helps to limit further irritation.

Zenrelia does not sedate dogs and it does not mask pain. Its role is to target the allergic component of skin disease. Because every dog and every allergy profile is different, your vet will assess how Zenrelia is working for your dog over time and may adapt the plan, including adding topical products or adjusting other treatments. If your dog’s symptoms change, or if you notice new signs such as ear headshaking, paw chewing, hot spots, or disturbed sleep, contact your vet for review.

Product Features

add remove
  • Pack Size: - Sold Individually
  • Target Animal: - Dog (Canine)
  • Related Condition: - allergic and atopic dermatitis in dogs
  • Pet Prescription Required?: - Yes
  • Active Ingredient: - ilunocitinib
  • Product Name: - 15mg Zenrelia Tablet for Dogs

More Information

add remove

Description

Vets consider Zenrelia for dogs with confirmed or strongly suspected atopic dermatitis or allergic dermatitis after ruling out other causes of itch, especially fleas and infections. It is often used when itch is frequent, intense, or affecting quality of life. The medicine can be used for short-term flares or for longer-term management, depending on the vet’s plan. It may be combined with medicated shampoos, ear treatments, topical anti-inflammatories, essential fatty acid support, and allergen-avoidance strategies. Dogs receiving Zenrelia should have regular veterinary check-ups so that control of the condition and overall wellbeing can be monitored.

Give Zenrelia exactly as directed by your veterinary surgeon. The tablets may be given with or without food unless your vet advises otherwise. Provide fresh water at all times. If you forget a dose, do not double the next one; resume the prescribed schedule and contact your vet if you are unsure. Do not use in dogs for which the vet has advised against immune-modulating treatments. Tell your vet about any other medicines or supplements your dog is taking so potential interactions can be considered. Use in breeding, pregnant, or lactating bitches should only occur if your vet decides the benefits outweigh the risks.

Most dogs tolerate 15mg Zenrelia well. As with any medicine, some dogs may experience side effects. These can include mild digestive upset such as vomiting, soft stools, or reduced appetite. Less commonly, changes in behaviour, increased thirst, or skin or ear issues can occur. Because allergic skin disease and its treatments can influence the skin’s natural defences, your vet may recommend periodic skin and ear checks, especially if your dog has a history of secondary infections. Seek veterinary advice promptly if you notice persistent vomiting or diarrhoea, lethargy, swelling, unusual bruising, cough, or any sign that concerns you.

Keep tablets in the original packaging, out of the sight and reach of children and animals. Store at room temperature and away from moisture. Do not use after the expiry date printed on the pack. Return unused or expired tablets to your pharmacy for safe disposal.

Atopy (atopic dermatitis) is a long-term allergic skin disease. Affected dogs have a heightened immune sensitivity to common environmental allergens. Typical triggers include grass and tree pollens, house dust mites, storage mites, mould spores, and sometimes fragments of insect proteins. Dogs cannot avoid many of these substances completely, so the immune system remains prone to flare ups, especially during certain seasons or in particular environments. Atopy often first appears in young adult dogs and can continue throughout life, with periods of stability and periods of increased itching.

Common signs include frequent scratching, chewing or licking of the paws, abdomen, groin, armpits, and face. Redness, rashes, recurrent ear problems, headshaking, and dark staining of the fur from saliva are typical. Over time, the skin can thicken, pigmentation may change, and the coat can become patchy. Because several different conditions can cause itch, diagnosis relies on a veterinary assessment. Your vet will take a full history, examine the skin and ears, rule out parasites and infections, and may recommend a diet trial to check for food-related skin reactions. Allergy testing can be used to identify relevant environmental allergens, especially when immunotherapy is being considered.

Management is individualised. The aim is to reduce itch quickly, protect the skin barrier, control secondary infections, and limit exposure to known triggers. Your vet may recommend:

  • Consistent flea control for all pets in the household. Even low-level flea exposure can worsen allergic skin disease.
  • Regular bathing with a veterinary-recommended shampoo to remove allergens from the coat and support the skin barrier.
  • Ear care to address wax, inflammation, or infection where needed.
  • Environmental measures such as frequent washing of bedding at high temperatures and vacuuming to reduce dust reservoirs.
  • Nutritional support, including diets formulated for skin health if appropriate.
  • Allergen-specific immunotherapy in selected cases, based on test results, to reduce sensitivity over time.
  • Prescription medicines, such as Zenrelia, to reduce the itch and inflammation that drive scratching and skin damage.

Because atopy is chronic, regular check-ups help to maintain control and adjust the plan as your dog’s needs evolve. Good day-to-day control reduces flare frequency, supports sleep and comfort, and helps prevent the self-trauma that leads to hot spots and infections. If you think a particular season, activity, or location triggers flares, record this and share it with your vet so targeted strategies can be considered.

Zenrelia is a prescription-only medicine. A valid veterinary prescription is required before we can dispense it. If you have questions about whether 15mg Zenrelia is suitable for your dog, please speak to your veterinary surgeon.

You may also like

16mg Apoquel for Dogs - Single Tablet

16mg Apoquel for Dogs - Single Tablet

16mg Apoquel for dogs is a prescription medication that is used to treat a variety of skin conditions in dogs. Apoquel works by blocking the signals that cause itching and inflammation, providing relief from symptoms associated with acute and chronic canine pruritus.

Canine pruritus (itchiness) is a condition that causes itching and inflammation of the skin in dogs. This condition can be caused by a variety of factors, including allergies, fleas, mites, and bacterial infections. Acute pruritus is a sudden onset of itching, while chronic pruritus is a more persistent form of itching that lasts for an extended period. Both types of pruritus can be debilitating for dogs, causing discomfort, pain, and even skin infections.

16mg Apoquel for dogs works by inhibiting the production of cytokines, which are molecules that contribute to inflammation and itching. By blocking these signals, Apoquel helps to reduce inflammation and provide relief from itching. Unlike other medications that suppress the immune system, Apoquel targets only the cells involved in the inflammatory response, minimizing the risk of side effects.

VET PRESCRIPTION REQUIRED

£2.22
4.8mg Zenrelia for Dogs - Per Tablet

4.8mg Zenrelia for Dogs - Per Tablet

4.8mg Zenrelia for Dogs

Zenrelia 4.8mg is a once-daily, tablet formulated for dogs aged twelve months and older to manage the itch and inflammation linked to allergic and atopic dermatitis. The active ingredient, ilunocitinib, acts as a non-selective Janus kinase (JAK) inhibitor. It works by interrupting key inflammatory signalling pathways that trigger itch sensations and skin irritation. Zenrelia is not a corticosteroid or antihistamine, but instead targets the underlying immune-mediated mechanisms that fuel pruritus and lesion formation.

Since ilunocitinib is rapidly absorbed and has a short half-life, the tablet begins to provide relief swiftly following administration and clears from the dog’s system within about 24 hours if treatment is paused. This pharmacokinetic profile offers dosing flexibility, permitting treatment to be initiated or stopped as needed, for instance, during diagnostic food trials without lingering drug accumulation.

4.8mg Zenrelia is designed for convenience and compliance. It can be administered with or without food and requires no loading dose or tapering phase. The scoring on the tablets in multiple strengths enables precise dosing from as low as approximately 0.6 mg per kilogram up to 0.8 mg per kilogram (0.27–0.36 mg per pound). This makes Zenrelia adaptable for dogs of different sizes and weight classes.

In clinical trials involving several hundred dogs with allergic or atopic dermatitis, Zenrelia demonstrated rapid reduction in itch scores and skin lesion severity, with outcomes comparable to or exceeding those of existing JAK inhibitors. Visual and numerical assessments showed notable improvements in both itching and inflammation within weeks of treatment commencement. The repeat-daily dosing maintained this effect over the longer term, supporting skin health and owner satisfaction.

VETERINARY PRESCRIPTION REQUIRED

£1.07
  • New
6.4mg Zenrelia for Dogs - Per Tablet

6.4mg Zenrelia for Dogs - Per Tablet

6.4mg Zenrelia is a once-daily, orally administered tablet containing ilunocitinib, a Janus kinase (JAK) inhibitor indicated for dogs from 12 months of age and weighing at least 3kg. It is formulated as a small, unflavoured film-coated tablet designed for ease of administration with or without food, with consistent dosing recommended at the same time each day.

Zenrelia works by inhibiting Janus kinase pathways involved in the inflammatory and pruritic signalling cascade. By targeting these pathways, Zenrelia reduces the biochemical processes that result in the characteristic itch and inflammation of allergic and atopic dermatitis. Following oral administration, it is rapidly absorbed, with visible improvements often appearing within 24 hours. While some dogs respond immediately, a full assessment of response should wait at least one week, with most showing notable improvement in itch and skin condition by two to four weeks.

Zenrelia 6.4mg is appropriate for use from the first veterinary consultation through diagnostic work-up and into long-term maintenance. Its simple, once-daily dosing implies that caregivers can begin treatment before a full diagnosis of atopic dermatitis, helping manage symptoms while underlying causes are explored and addressed.

VETERINARY PRESCRIPTION REQUIRED

£0.77
  • New