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Apoquel 5.4mg tablets contain oclacitinib, a veterinary medicine used in dogs to control itching (pruritus) associated with allergic skin disease. Apoquel is commonly prescribed for dogs with allergic dermatitis, including canine atopic dermatitis, where inflammation and itch can become persistent. The 5.4mg strength is selected by a veterinary surgeon based on your dog’s bodyweight and treatment plan.

What Apoquel 5.4mg is used for

Apoquel is used to help control:
• Acute pruritus (sudden onset itching) linked to allergic dermatitis.
• Chronic pruritus (long-term or recurring itching) linked to allergic dermatitis, including canine atopic dermatitis.

Itching is a symptom rather than a diagnosis. A veterinary assessment is important to identify likely triggers, check for parasites or infection, and decide whether Apoquel is appropriate.

How Apoquel works

Allergic skin problems in dogs are driven by chemical messengers in the immune system. These messengers, often called cytokines, help coordinate inflammation and the sensation of itch. In allergic dermatitis, this signalling can become overactive, leading to redness, irritation, and scratching.

Oclacitinib works by targeting specific signalling pathways inside immune cells known as Janus kinases (JAKs). By reducing JAK-dependent signalling, Apoquel helps lower the activity of itch-promoting and inflammation-promoting cytokines. This can reduce the urge to scratch and can calm skin inflammation, which helps break the itch–scratch cycle that can damage the skin barrier.

Because it acts on immune signalling, Apoquel does not remove allergens from the environment, and it does not treat the root cause of parasites or infection. It is often used alongside an overall plan that may include flea control, skin care, diet management, and treatment of secondary bacterial or yeast infection where needed.

100mg Pexion is a treatment for dogs with primary epilepsy. Pexion acts on a specific receptor in the brain cells to reduce the amount of excessive electrical activity present.

Pexion is is specifically designed to reduce the number of seizures your dog has and the impact they have on your dog’s life. This can mean a more normal life for them, less disruption to you, and less stress for the whole family.

VET PRESCRIPION REQUIRED

10mg Cardisure is used for the treatment of canine congestive heart failure originating from valvular insufficiency (mitral and/or tricuspid regurgitation) or dilated cardiomyopathy.

Cardisure 10mg is a medicine that can help to treat congestive heart failure in dogs. Cardisure contains pimobendan, which is a phosphodiesterase III inhibitor. Cardisure can help to improve the ability of the heart to pump blood around the body. It can also increase the amount of oxygen that the heart can provide to your dog's body.

VET PRESCRIPTION REQUIRED

Incurin is a prescription medication used to manage hormone-dependent urinary incontinence in female dogs. It contains estriol, a natural form of oestrogen, which helps restore control over bladder function. This medication is specifically designed for spayed female dogs experiencing involuntary urine leakage due to decreased oestrogen levels.

What is Hormone-Dependent Urinary Incontinence?

Hormone-dependent urinary incontinence is a common condition in spayed female dogs, typically occurring as they age. It results from a decline in oestrogen production following spaying. Oestrogen plays a crucial role in maintaining muscle tone in the urethral sphincter, which is responsible for preventing urine leakage.

When oestrogen levels drop, the muscles controlling urine retention weaken, leading to involuntary leakage. This condition is also known as urethral sphincter mechanism incompetence (USMI). It can cause noticeable symptoms such as small puddles of urine left behind where the dog has been lying down or sleeping. Leakage can be infrequent or more consistent, depending on the severity of the condition.

Although the condition is not painful, it can be distressing for both the dog and the owner. Affected dogs may not realise they are leaking urine, and owners may notice damp bedding or an ammonia-like odour. Without treatment, the condition can lead to skin irritation, infections, and hygiene concerns.

Libromide is a veterinary medicine used to help manage epilepsy in dogs. Libromide Tablets are commonly prescribed by veterinary surgeons for the long-term treatment of canine epilepsy, especially in cases where phenobarbital alone is not effective or suitable. 325mg Libromide contains the active ingredient potassium bromide, which has anticonvulsant properties. It is used either as a standalone treatment or in combination with other anti-epileptic medications to help reduce the frequency and severity of seizures in dogs.

Epilepsy is a neurological condition that affects the brain. In dogs, it leads to recurrent seizures, which can vary in type and severity. The exact cause of epilepsy is often unknown, particularly in cases of idiopathic epilepsy, which is the most common form in dogs. However, the condition can also result from underlying health issues such as brain tumours, liver disease, head trauma, or exposure to toxins. Regardless of the cause, the goal of treatment is to reduce seizure frequency and improve the dog’s quality of life.

Seizures are caused by abnormal electrical activity in the brain. When nerve cells (neurons) fire excessively or erratically, this can result in uncontrolled muscle movements, loss of consciousness, drooling, twitching, or other physical symptoms. In dogs with epilepsy, this activity can be triggered randomly and may occur multiple times a month or even several times in a single day. Not all seizures are the same. Some may involve the whole body (generalised seizures), while others may only affect part of the body or behaviour (focal seizures).

Libromide Tablets work by stabilising the electrical activity in the brain. Potassium bromide, the active ingredient, alters the chloride transport within neurons, increasing the seizure threshold and reducing the likelihood of seizures occurring. This helps to calm the nerve signals in the brain, making seizures less frequent and less intense. Unlike some medications, Libromide is not metabolised by the liver, which makes it a useful alternative for dogs with liver conditions or those who do not tolerate phenobarbital well.

VET PRESCRIPTION REQUIRED

Onsior 40mg for Dogs is a prescription-only non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in dogs. It contains the active substance robenacoxib, which is a selective cyclooxygenase-2 (COX-2) inhibitor. This medicine is commonly prescribed by vets to manage pain associated with osteoarthritis and musculoskeletal disorders in dogs.

Each tablet contains 40mg of robenacoxib and is designed for once-daily oral administration. Onsior tablets are flavoured to aid with administration and are scored to allow accurate dosing based on the dog’s weight. They are authorised for veterinary use in the UK and have been shown to be effective for the management of chronic and acute pain.

How 40mg Onsior Works

Onsior 40mg contains robenacoxib, a member of the coxib class of NSAIDs. It works by selectively inhibiting the enzyme cyclooxygenase-2 (COX-2), which plays a key role in producing prostaglandins responsible for pain and inflammation. By blocking COX-2, robenacoxib reduces the production of these chemicals at the site of injury or inflammation.

Unlike traditional NSAIDs, Onsior has minimal effect on COX-1, the enzyme involved in maintaining normal functions of the gastrointestinal tract, kidneys, and blood clotting. This selectivity helps reduce the risk of gastrointestinal and renal side effects often associated with NSAID use in dogs.

Onsior begins to act rapidly, with effects typically observed within one to two hours of administration. The drug accumulates preferentially at sites of inflammation, allowing for targeted relief of pain while limiting exposure to unaffected tissues.

VET PRESCRIPTION REQUIRED

Amodip 1.25mg for Cats is a prescription-only medication used to manage systemic hypertension (high blood pressure) in cats. It contains the active ingredient amlodipine besylate, which belongs to a class of medicines called calcium channel blockers. This medicine is widely used in veterinary medicine to help reduce and control blood pressure in feline patients.

Amodip comes in chewable tablets that are flavoured to make administration easier. Each tablet contains 1.25mg of amlodipine, which is the most commonly recommended starting dose for cats. It is licensed for veterinary use in the UK and is usually prescribed by vets when a cat has been diagnosed with persistent high blood pressure.

How Amodip Works

Amodip works by relaxing the smooth muscles of the blood vessel walls. It does this by inhibiting the movement of calcium into the cells of the heart and blood vessels. This relaxation causes the vessels to widen (vasodilation), which lowers the resistance against blood flow and helps reduce blood pressure.

Lowering blood pressure reduces the strain on the heart and can help prevent damage to organs such as the kidneys, brain, and eyes. In cats, high blood pressure can lead to serious health issues including blindness, seizures, and kidney failure. By maintaining blood pressure within a normal range, Amodip can support long-term health and improve a cat's quality of life.

VET PRESCRIPTION REQUIRED

15mg Zenrelia for Dogs

15mg Zenrelia for Dogs is a prescription medicine used to help manage the itch and skin inflammation associated with allergic skin disease, including atopic dermatitis (atopy). Zenrelia is intended for dogs that have been examined by a veterinary surgeon and diagnosed with an allergic condition. Zenrelia 15mg is used as part of a wider care plan that may include parasite control, skin and ear care, environmental changes, and nutrition.

How Zenrelia for Dogs works

Zenrelia acts on the pathways that drive itch and inflammation during an allergic flare. In dogs with atopy, the immune system reacts strongly to otherwise harmless substances such as pollen, house dust mites, moulds, or other environmental allergens. This reaction releases chemical messengers that signal itch, redness, heat, and swelling in the skin. Zenrelia Tablets help to reduce these signals. By moderating the activity of key immune messengers and the cells that release them, the medicine lowers the intensity of the itch response and helps calm inflamed skin. As the impulse to scratch and lick reduces, the skin surface has a better chance to recover, which in turn helps to limit further irritation.

Zenrelia does not sedate dogs and it does not mask pain. Its role is to target the allergic component of skin disease. Because every dog and every allergy profile is different, your vet will assess how Zenrelia is working for your dog over time and may adapt the plan, including adding topical products or adjusting other treatments. If your dog’s symptoms change, or if you notice new signs such as ear headshaking, paw chewing, hot spots, or disturbed sleep, contact your vet for review.

VETERINARY PRESCRIPTION REQUIRED

0.75mg Upcard contains torasemide, a once daily, flavoured, easily-divisible loop diuretic for dogs.

Upcard 0.75mg Tablets are an innovative treatment for congestive heart failure in dogs. They contain the active ingredient Torasemide, which is a loop-diuretic to treat fluid overload due to heart failure, kidney failure, liver disease and high blood pressure.

VETERINARY PRESCRIPTION REQUIRED

15mg Palladia for Dogs - Treatment for Canine Mast Cell Tumours

Mast cell tumours, a common type of cancer in dogs, account for a large portion of all canine skin tumours. These malignant growths originate from mast cells, a type of white blood cell. Early detection and proper treatment are vital in managing this condition, and 15mg Palladia for dogs offers a highly effective solution.

Palladia 15mg for dogs works by targeting specific proteins involved in the growth and spread of cancerous cells. The drug inhibits the activity of these proteins, effectively stopping tumour progression. This targeted approach allows 15mg Palladia to attack cancerous cells while sparing healthy ones, minimising overall side effects on your pet.

VET PRESCRIPTION REQUIRED

7.5mg Upcard contains torasemide, a once daily, flavoured, easily-divisible loop diuretic for dogs. VETERINARY PRESCRIPTION REQUIRED

5mg Fortekor Flavoured is a heart failure treatment for dogs. It contains the active ingredient benazepril hydrochloride.

Fortekor 5mg is given orally and is broken down into an efficient inhibitor of angiotensin-converting enzyme (ACE), reducing blood volume, sodium and water levels, as well as making it harder for your dog's heart to pump effectively.

VET PRESCRIPTION REQUIRED