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2.5mg Cardisan for Dogs is a veterinary prescription medicine used to support dogs with certain types of chronic heart disease, when the heart is no longer pumping as efficiently as it should. The chewable tablet can help make daily dosing straightforward. It is most often prescribed for congestive heart failure linked to myxomatous mitral valve disease (a “leaky” mitral valve common in smaller breeds) or dilated cardiomyopathy (a weakened, enlarged heart muscle more often seen in larger breeds).

The active ingredient in 2.5mg Cardisan is pimobendan, often described clinically as an “inodilator”. That means it helps the heart contract more strongly (a positive inotrope) and helps blood vessels relax (vasodilation). Cardisan helps create a stronger squeeze and an easier flow, so the heart does not have to work as hard to move blood forward. Pimobendan makes the heart muscle more sensitive to calcium inside the cells, improving pumping efficiency without simply driving the heart rate up. It also has a mild effect on an enzyme called phosphodiesterase‑3 (PDE‑3), which encourages blood vessels to widen. Together, these effects can increase cardiac output and reduce the “back pressure” that worsens mitral valve leakage and encourages fluid to seep into the lungs. 2.5mg Cardisan is not a diuretic and it does not “dry out” fluid on its own, but it often works well as part of a combined plan to improve circulation and breathing comfort.

1.25mg Cardisan for Dogs is a prescription heart medication used when a dog needs support because the heart is not pumping blood efficiently. Veterinary surgeons may prescribe 1.25mg Cardisan for dogs with certain types of heart disease that can lead to poor circulation and fluid build-up, particularly when signs are starting to affect day-to-day comfort. The 1.25mg strength is often chosen for smaller dogs, for careful dose adjustments, or when a lower starting dose is appropriate before reviewing response.

Cardisan for Dogs works by improving the efficiency of the heart’s pumping action while also making it easier for blood to flow through the circulation. The active ingredient, pimobendan, increases the strength of contraction so each heartbeat can move more blood forward, and it also promotes gentle widening of blood vessels. These combined effects are sometimes described as an "inodilator" action, because the medicine supports inotropy (contractility) and vasodilation at the same time. By lowering the resistance the heart must pump against, 1.25mg Cardisan can reduce workload and may help the heart deliver oxygenated blood to the body with less strain. In dogs with heart failure, this can contribute to improved exercise tolerance and more comfortable breathing, especially when used alongside other therapies chosen by your vet.

Audevard Ekycush Control is a nutritional supplement designed for horses and ponies that need extra, everyday support when their hormone balance begins to change with age. It is most often considered for animals affected by Pituitary Pars Intermedia Dysfunction (PPID), commonly called Cushing's in horses, where the body's normal hormonal signals and stress response can become less steady over time.

Ekycush Control is intended to be fed daily and used as part of a wider management plan agreed with your veterinary surgeon. It is not a substitute for diagnosis or prescription treatment, but it can help provide consistent nutritional support for horses with early signs or a confirmed diagnosis. Horses with PPID often need support in several areas at once, including coat and skin changes, muscle loss, and an increased risk of hoof soreness. Ekycush Control fits best alongside sensible diet choices and regular monitoring, so that small changes are spotted early.

PPID develops when the pituitary gland, a small hormone-producing gland at the base of the brain, becomes overactive, particularly in the area known as the pars intermedia. In a healthy horse, dopamine helps keep this area under control. With PPID, that natural dopamine control reduces, so the gland produces higher levels of certain hormones, including ACTH, and the horse's internal balance starts to shift. The signs can be subtle at first, and they do not always appear all at once. A mild change in coat, slower recovery after work, or unexplained 'footiness' can be an early clue, especially in an older pony. Some horses grow a longer or curlier coat, shed later than expected, or sweat in cooler weather. Others seem dull, lose topline muscle, or develop a pot-bellied outline even when their feed has not changed. Increased drinking and urination can occur, and some horses develop repeated infections or skin problems that keep returning.

Diagnosis is usually based on clinical signs alongside blood testing, and your vet may recommend repeating tests at certain times of year because hormone levels can vary seasonally. Ekycush Control is designed for the practical, day-to-day side of that management once PPID is suspected or confirmed. 900g

Douxo S3 Calm Shampoo Bar is a solid bar veterinary skincare cleanser designed for dogs and cats with sensitive, reactive or easily irritated skin. The solid bar format offers a practical way to wash a pet that dislikes long baths, while still delivering a thorough, gentle clean from skin to tip.

Douxo S3 Calm Shampoo Bar is intended for pets that scratch, lick, rub their face, or seem restless because their skin feels uncomfortable, particularly when dryness, environmental allergens or repeated washing have left the coat feeling tight and the skin looking pink, flaky or slightly scurfy. Because the bar glides directly over the coat, Douxo S3 Calm Shampoo Bar can be applied evenly across the body or focused on problem areas such as the chest, belly, paws and folds, without using large amounts of product. It is a supportive hygiene step for ongoing skin care, and it can be especially helpful when you want a calming wash that is easy to handle in the shower, bath or grooming area.

Itchy skin in pets often reflects a weakened skin barrier. When the outer layers of the skin do not hold on to moisture properly, the surface dries out and becomes more permeable, so everyday triggers such as pollen, house dust, grooming residues and hard water can sting or inflame. Scratching can feel relieving in the moment, but it also damages the barrier further, creating an itch–scratch cycle that is difficult to break. At the same time, irritation can disturb the skin’s normal balance, which may increase odour and leave the skin less resilient during flare-ups.

Rather than relying on harsh degreasing, Douxo S3 Calm Shampoo Bar aims to clean with a mild lather and then support comfort by helping the skin stay hydrated and better defended after rinsing. This approach is useful for pets whose skin reacts quickly to change, including those with seasonal itching or ongoing sensitivity that needs steady, low-irritant care. 100g

Trilocur 50ml Oral Suspension for Dogs is a veterinary medicine used to manage hyperadrenocorticism, often called Cushing’s disease, in dogs. With this condition the body produces too much cortisol for months or years, and the effects can build up gradually. Many owners first notice that their dog drinks far more than normal and needs to urinate more often, including asking to go outside at night or having accidents in the house. Increased appetite, weight gain around the abdomen, heavier panting, and reduced stamina are also common. Some dogs develop thinning hair, fragile skin, or recurrent ear and skin problems, while others seem less interested in exercise or play. Because these signs can overlap with other illnesses, your vet will usually confirm hyperadrenocorticism with a combination of history, examination and laboratory tests before starting Trilocur. Some dogs seem restless and pace, while others become quieter and less keen to exercise. Skin and coat changes can develop over time, including thinning hair, recurrent skin infections, slow hair regrowth after clipping, and fragile skin that bruises easily. Because these signs can overlap with other illnesses, diagnosis and treatment decisions should always be made by a vet, and Trilocur should only be used under veterinary direction.

Trilocur contains trilostane, a medicine that reduces cortisol production within the adrenal glands. Trilostane works by blocking an enzyme involved in making steroid hormones, so the adrenal glands produce less cortisol and release less into the bloodstream. The effect is reversible, which is helpful because your vet can adjust the dose if cortisol control is not adequate or if the effect becomes too strong. Trilocur does not remove the underlying cause of Cushing’s disease, but by lowering cortisol it can reduce the impact of the disease and help a dog feel more comfortable day to day. When Trilocur is working well, owners often notice steadier drinking and urination patterns, less panting, and an improved level of energy. Coat and skin improvements can take longer and tend to be more gradual. The goal is stable control over time, rather than rapid change in a few days.

25ml Trilocur for Dogs (trilostane oral suspension) is a prescription-only medicine used to help manage hyperadrenocorticism, commonly called Cushing’s disease. It is intended for dogs diagnosed by a veterinary surgeon and supplied as an oral liquid that can be measured accurately to match the prescribed dose.

Trilocur contains trilostane. 25ml Trilocur reduces the production of steroid hormones made by the adrenal glands, particularly cortisol. In dogs with Cushing’s disease, cortisol levels are higher than the body needs. Excess cortisol disrupts normal metabolism and immune function and can affect many organs over time. By lowering cortisol production, trilostane can help control clinical signs and improve day-to-day comfort.

How Trilocur works

The adrenal glands sit close to the kidneys and produce several important hormones, including cortisol. Cortisol helps the body respond to stress, regulates the use of fat, protein and carbohydrates, supports blood pressure, and influences the immune system. In Cushing’s disease, cortisol is produced in excess, either because the pituitary gland is stimulating the adrenals too strongly or because an adrenal tumour is producing hormones directly.

Trilocur blocks an enzyme involved in the adrenal gland’s steroid production pathway (3β-hydroxysteroid dehydrogenase). This reduces the synthesis of cortisol and related adrenal steroids. The aim of treatment is not to remove cortisol completely, but to bring production back into a controlled range. Because dogs respond differently, dosing and monitoring are important, especially early on and after any dose changes.

Trilocur may be prescribed for:
- Pituitary-dependent hyperadrenocorticism (the most common form), where a pituitary change increases ACTH stimulation of the adrenal glands.
- Adrenal-dependent hyperadrenocorticism, where an adrenal tumour produces excess hormones.